by Rod Pearson
Tuesday, Oct 21, 2025
Game Time: 1:00 pm ET, Sunday, October 26, 2025
Venue: Gillette Stadium, Foxborough, MA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Browns +7, Patriots -7; Over/Under: 40.5 points
Bet365: Point Spread: Browns +7, Patriots -7; Over/Under: 40.5 points
BetMGM: Point Spread: Browns +7, Patriots -7; Over/Under: 40.5 points
Season Record
Cleveland Browns: 2-5 (3rd place, AFC North)
New England Patriots: 5-2 (1st place, AFC East)
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Recent Form
Cleveland Browns: won their last game at home against the Miami Dolphins 31-6.
New England Patriots: won their last game on the road against the Tennessee Titans 31-13.
Cleveland Browns vs New England Patriots Preview and Analysis
The Browns are entering this game with a 2-5 record overall and they have a 0-3 record in their divisional games too. They are 2-1 in their home games, 0-3 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Miami Dolphins 31-6. Dillon Gabriel was the starting QB and he completed 13/18 passes for 116 passing yards, 0 touchdowns, and 0 interceptions. Quinshon Judkins led the team in rushing yards with 84 and 3 TDs. Harold Fannin Jr. led the receivers with 36 receiving yards on 4 receptions. Alex Wright led the defense in that game with 4 solo tackles and 1 assisted tackle while Myles Garrett, Grant Delpit, Donovan McMillon, and Jerome Baker each led the defense in sacks with 1. Rayshawn Jenkins, Tyson Campbell, and Ronnie Hickman each came away with 1 interception for them in that one.
The Patriots are entering this game with a 5-2 record overall and they have a 2-0 record in their divisional games too. They are 1-2 in their home games, 4-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Tennessee Titans 31-13. Drake Maye was the starting QB and he completed 21/23 passes for 222 passing yards, 2 touchdowns, and 0 interceptions. Rhamondre Stevenson led the team in rushing yards with 88 and 1 TD. Stefon Diggs led the receivers with 69 receiving yards on 7 receptions. Marte Mapu led the defense in that game with 6 solo tackles and 2 assisted tackles while K'Lavon Chaisson led the defense in sacks with 2. Marcus Jones came away with the only interception for them in that one.
Browns vs Patriots Prediction
The current betting odds have the Patriots listed as a 7 point favorite in this game according to Draftkings Sportsbook. The Patriots have looked great in their games this season with their 5-2 record overall which has them right at the top of the AFC East. They had a rough start to the season, but they have won 4 games in a row now and have been rolling. The offense has looked great with Drake Maye starting to have a break out season and Mike Vrabel has this team pointed in the right direction in his 1st year. Meanwhile, the Browns haven't looked good in their games this season with their 2-5 record overall which has them right near the bottom of the AFC North. They are off a 31-6 win over the Dolphins in their last one, but they were beating up on a team that has been a disaster all season. The Browns do have a really good defense, but their offense has looked terrible. They looked better in that last game against one of the worst defenses in the NFL, but the Browns have also looked a lot better in their home games this year too. They have looked like a different team in their road games, their offense looking even worse in those, and the Patriots defense has looked a lot better lately. This is going to be another game where the Browns struggle offensively on the road and their defense will only be able to hang on for so long before the Patriots pull away. The best way to place a bet here is on the Patriots to cover the spread in this game.
Browns Patriots Prediction: Our NFL Pick for Sunday, October 26, 2025 (1:00 pm ET start time) is Patriots 34 Browns 17.
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NFL Betting Trends
Cleveland Browns: 5-16 ATS in road games. 3-8 ATS off a home win. 6-12 ATS after playing a game at home. 4-8 ATS vs. good offensive teams - scoring 24 or more points/game. 14-7 OVER in road games. 10-4 OVER in a road game where the total is between 35.5 and 42 points.
New England Patriots: 44-30 ATS against AFC North division opponents. 48-33 ATS after 3 or more consecutive wins against the spread. 38-29 ATS versus good defensive teams - allowing 285 yards/game or less. 8-4 OVER in a home game where the total is between 35.5 and 42 points.
Key Injuries
Cleveland Browns: J. Conklin (OT) Injured - NIR - Rest. E. Pocic (C) Injured - Illness. R. Jenkins (S) Injured - Wrist. J. Jeudy (WR) Injured - Knee. D. Njoku (TE) Injured - Knee. D. Ward (CB) Injured - Hip. B. Whiteheart (TE) Injured - Shoulder. J. Bitonio (OG) Injured - NIR-Rest. T. Campbell (CB) Injured - Quad. M. Collins (DL) Injured - NIR-Rest. G. Delpit (S) Injured - Toe. M. Graham (DL) Injured - Knee. M. Hall Jr. (DL) Injured - Knee. S. Harris (DL) Injured - Knee. A. Huntington (DL) Injured - Concussion.
New England Patriots: K. Dugger (S) Injured - Knee. E. Ponder (LB) Injured - Knee. C. Woodson (S) Injured - Ankle. H. Landry III (LB) Injured - Ankle. C. Barmore (DL) Injured - NIR - Other. S. Diggs (WR) Injured - Chest. M. Moses (OT) Injured - NIR - Other. K. Tonga (DL) Injured - Knee. C. Gonzalez (CB) Injured - Hamstring. J. Hawkins (S) Injured - Hamstring. C. Woods (CB) Injured - Knee.
Notable Quotes
“We always talk about complementary football, but seeing us all come together is important and good to see.” - Dillon Gabriel after their win against the Dolphins in their last game.
“I didn’t get that many tickets, I don’t know. I’m happy for our players. I think these guys they’re figuring out how to win, they’re figuring out how to practice. I guess it’s humbling to have these people whoever that is cheer for us whether that's the Patriots or Drake Maye or me or anybody else." - Mike Vrabel after his team’s win against the Titans in their last game.
Starting Lineups
Cleveland Browns
WR Jeudy, Jerry
WR Thrash, Jamari
WR Bond, Isaiah
TE Fannin Jr., Harold
QB Gabriel, Dillon
RB Judkins, Quinshon
New England Patriots
WR Boutte, Kayshon
WR Hollins, Mack
WR Diggs, Stefon
TE Henry, Hunter
QB Maye, Drake
RB Stevenson, Rhamondre
FB Westover, Jack
Statistical Leaders
Cleveland Browns
Passing: Joe Flacco (815)
Rushing: Quinshon Judkins (467)
Receiving: Harold Fannin Jr. (290)
Touchdowns: Quinshon Judkins (5)
New England Patriots
Passing: Drake Maye (1,744)
Rushing: Rhamondre Stevenson (245)
Receiving: Stefon Diggs (456)
Touchdowns: Kayshon Boutte (4)
Coaches:
Cleveland Browns: Kevin Stefanski (6th season)
New England Patriots: Mike Vrabel (1st season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
