Clemson Tigers vs Duke Blue Devils Prediction, Picks and Game Preview - 02/14/2026

Game Time: 12:00 pm ET, Saturday, February 14, 2026

Venue:  Cameron Indoor Stadium, Durham, NC

Where to Watch:  ESPN

DraftKings:  Point Spread:  Clemson +12.5, Duke -12.5; Over/Under:  133.5 points

Bet365:  Point Spread:  Clemson +12.5, Duke -12.5; Over/Under:  133.5 points

BetMGM:  Point Spread:  Clemson +12.5, Duke -12.5; Over/Under:  133.5 points

Clemson Tigers:  20-5 (10-2) (3rd place, ACC)

Duke Blue Devils:  22-2 (11-1) (1st place, ACC)

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Clemson Tigers:  4-1  last 5

Duke Blue Devils:  4-1  last 5

Clemson is entering this game with a 20-5 record overall, a 10-2 record in conference games, and they are 6-2 in their road games this season where they will be in this game. They are coming off a loss against the Virginia Tech Hokies in their last game. Carter Welling led the team in points in that game with 19 while Nick Davidson and Ace Buckner each were next on the team with 16. RJ Godfrey and Ace Buckner each led the team in assists with 2 in that game while Carter Welling led the team in rebounds with 6. They were 45.5% from the field, 31.3% from 3-point range, and 61.1% from the free throw line with their shooting in that game. Their offense is averaging 75.6 PPG and their defense is allowing their opponents to average 64.6 PPG against them. Clemson has an ATS record of 13-10-1 this season and their O/U record is 9-15.

Duke is entering this game with a 22-2 record overall, a 11-1 conference record, and they are 11-0 in their home games this season where they will be in this game. They are coming off a win against the Pittsburgh Panthers in their last game. Isaiah Evans led the team in points in that game with 21 while Cameron Boozer was next on the team with 17. Caleb Foster led the team in assists with 5 in that game while Cameron Boozer led the team in rebounds with 10. They were 54.9% from the field, 39.1% from 3-point range, and 62.5% from the free throw line with their shooting in that game. Their offense is averaging 82.9 PPG and their defense is allowing their opponents to average 63.6 PPG against them. Duke has an ATS record of 13-11 this season and their O/U record is 7-17.

The current betting odds have Duke listed as a 12.5 point favorite in this game according to Draftkings Sportsbook. Duke has looked great in their games this season with their 22-2 record overall and their 11-1 conference record which has them right at the top of the ACC. They have looked great on their home court too with their 11-0 home record this season. Meanwhile, Clemson has looked really good in their games this season with their 20-5 record overall and their 10-2 conference record which has them right near the top of the ACC. They have been a good road team too with their 6-2 road record this year. Clemson is 4-1 in their last 5 games and they have looked like one of the best teams in the ACC this year, but they are off a bad home loss to Virginia Tech in their last one and they haven't faced many of the elite teams in the ACC yet. Duke is also 4-1 in their last 5 games and they just took a tight loss on the road against their rival UNC, but they did bounce back with a big road win over Pittsburgh in their last one. They won that game by double digits and that has been a common theme for them this year as they have been blowing out many of their opponents in the ACC by large margins. Clemson will be looking to bounce back here, but this is a tough game to bounce back on the road against one of the best teams in the nation. Clemson has also struggled against some of the weaker teams in the ACC this year, so there is a chance that they start to regress now as the schedule gets tougher. Duke has also blown out some really good ranked teams this season, so look for them to continue rolling here. The best way to place a bet here is on Duke to cover the spread in this game. 

Clemson Duke Prediction:  Our NCAAB Pick for Saturday, February 14, 2026 (12:00 pm ET start time) is Duke 82 Clemson 66.

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Clemson Tigers: 14-4 ATS as an underdog. 8-3 ATS off an upset loss to a conference rival as a favorite. 21-11 ATS versus good rebounding teams - outrebounding opponents by 4+ per game. 9-5 UNDER off a loss against a conference rival.

Duke Blue Devils: 5-11 ATS after 3 or more consecutive unders. 4-9 ATS at home off a road win. 3-8 ATS at home off a road win against a conference rival. 5-1 UNDER as a home favorite of 6.5 to 12 points. 23-14 UNDER when playing against a good team (Win Pct. 60% to 80%).

Clemson Tigers:  Z. Foster (G) Out - Knee.

Duke Blue Devils:  P. Ngongba (C) Questionable - Undisclosed. I. Ufochukwu (C) Out - Undisclosed. S. Wilkins (G-F) Out - Redshirt.

“The story is not that Clemson came back from the West Coast and whatever. We got beat by a good team tonight that outplayed us. No excuses.” - Brad Brownell after his team’s loss against VA Tech in their last game. 

"I'm really proud of our guys. We had some lineups out there we never practiced, let alone played in a game. I thought our defense really carried the way for us. A bunch of different guys stepped up and proud to get this win but more importantly, it's about a response. Whether we won or lost Saturday, you know the biggest battle is getting over to the next one. Each game is worth one, and we want to just get this done and put ourselves in position to play for first place on Saturday." - Jon Scheyer after his team’s win against Pitt in their last game. 

R. Godfrey 

D. Hunter 

J. Porter 

J. Wahlin 

C. Welling

C. Boozer 

I. Evans 

C. Foster 

P. Ngongba 

D. Sarr

PPG: RJ Godfrey (11.6)

APG: Dillon Hunter (3)

Reb/G: Carter Welling (5.7)

PPG: Cameron Boozer (23)

APG: Cameron Boozer (4)

Reb/G: Cameron Boozer (10)

Coaches:

Clemson Tigers: Brad Brownell (16th season)

Duke Blue Devils: Jon Scheyer (4th season)