by Rod Pearson
Tuesday, Aug 19, 2025
Game Time: 9:38 pm ET, Wednesday, August 20, 2025
Venue: Angel Stadium, Anaheim, CA
Where to Watch: MLBN
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Reds +104, Angels -126; Over/Under: 8.5 runs
Bet365: Moneyline odds: Reds +105, Angels -125; Over/Under: 8.5 runs
BetMGM: Moneyline odds: Reds +105, Angels -125; Over/Under: 8.5 runs
Season Record
Cincinnati Reds: 66-60 (3rd place, NL Central)
Los Angeles Angels: 60-65 (4th place, AL West)
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Recent Form
Cincinnati Reds: 6-4 last 10
Los Angeles Angels: 5-5 last 10
Cincinnati Reds vs Los Angeles Angels Preview and Analysis
The Reds are entering this series off a win and lost their 3-game series against the Milwaukee Brewers 2-1 in their last series. They enter this game with a 66-60 record overall and have a road record of 30-31. This is the series finale of a 3-game series with the Angels on Wednesday with the 2nd game still to be played on Tuesday. The Reds won the series opener on Monday. Their offense ranks 19th in the MLB with a .710 OPS. Hunter Greene is their starting pitcher on Tuesday while Nick Martinez is making his start in this game on Wednesday. He is 10-9 with a 4.73 ERA this season. His team won 6 of their last 7 games this season with him making an appearance. In his last MLB regular season start, he allowed 5 ER, 2 HR, and 0 BB with 1 SO on 9 hits through 2.2 IP against the Milwaukee Brewers.
The Angels are entering this series off a win and lost their 3-game series against the Athletics 2-1 in their last series. They enter this game with a 60-65 record overall and have a home record of 33-31. This is the 3rd game of a 3-game series with the Reds on Wednesday with the 2nd game of this series still to be played on Tuesday. The Angels lost the 1st game of this series on Monday. Their offense ranks 14th in the MLB with a .714 OPS. Kyle Hendricks is their starting pitcher on Tuesday while Yusei Kikuchi is making his start in this game on Wednesday. He is 6-8 with a 3.52 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 4 earned runs, 2 homers, and 3 walks with 3 strikeouts on 5 hits through 4 innings pitched against the Athletics.
Reds vs Angels Prediction
The current betting odds have the Angels listed as a slight favorite in this game according to Draftkings Sportsbook. The Reds have looked good in their games this season with their 66-60 record overall which has them right in the middle of the NL Central and in the Wild Card race. They haven't been a great road team though with their 30-31 road record. Meanwhile, the Angels haven't looked good in their games this season with their 60-65 record overall which has them right near the bottom of the AL West. They have looked better in their own ballpark though with their 33-31 home record this year. The Angels haven't been the better team lately as they are 5-5 in their last 10 games while the Reds are 6-4, but the Angels do have the better pitching matchup in this one and can take advantage of that. The Angels are going with Kikuchi in this one and he has looked great this season. He is 6-8 with a 3.52 ERA and he hasn't been giving up a ton of runs this year. He did give up 4 earned runs in his last start, but that hasn't been a common theme for him, and the team has still had lots of success as they have won 3 of their last 4 games with him starting. The Reds are going with Martinez in this one and he hasn't looked great this season. He is 10-9 with a 4.73 ERA and has been giving up quite a few runs all year, but the team has still had a ton of success with him lately. They have won 6 of their last 7 games with him starting, but he is coming off another bad start in which he gave up 5 earned runs which has been a common theme for him this year so his good fortune is starting to come to an end now. Look for the Angels to take advantage of the better pitching matchup in this one. The best way to place a bet here is on the Angels to win this game.
Reds Angels Prediction: Our MLB Pick for Wednesday, August 20, 2025 (9:38 pm ET start time) is Angels 6 Reds 5.
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MLB Betting Trends
Cincinnati Reds: 24-15 (+11.2 units) on the moneyline against AL West opponents. 224-225 (+13.3 units) on the moneyline in all games. 112-111 (+26.6 units) on the moneyline in road games. 22-9 UNDER vs. an AL starting pitcher whose ERA is 3.70 or better.
Los Angeles Angels: 196-253 (-25.2 units) on the moneyline in all games. 103-123 (-22.8 units) on the moneyline in home games. 76-102 (-25.8 units) on the moneyline when the money line is +125 to -125. 34-21 UNDER as a home favorite of -125 to -175.
Key Injuries
Cincinnati Reds: C. Burns (SP) Fifteen Day IL - Elbow. N. Lodolo (SP) Fifteen Day IL - Finger. W. Miley (SP) Sixty Day IL - Flexor. I. Gibaut (RP) Fifteen Day IL - Shoulder. R. Lowder (SP) Sixty Day IL - Forearm. C. Spiers (RP) Sixty Day IL - Shoulder. T. Callihan (LF) Sixty Day IL - Forearm. B. Williamson (SP) Sixty Day IL - Elbow. J. Aguiar (SP) Sixty Day IL - Elbow.
Los Angeles Angels: G. Campero (RF) Ten Day IL - Ankle. C. Taylor (CF) Ten Day IL - Hand. J. Soler (RF) Ten Day IL - Back. R. Stephenson (RP) Sixty Day IL - Bicep. H. Strickland (RP) Sixty Day IL - Shoulder. B. Joyce (RP) Sixty Day IL - Shoulder. A. Rendon (3B) Sixty Day IL - Hip.
Notable Quotes
“I don’t think it’s any bit productive to look down the road and see who we’re playing three weeks from now. We might miss what’s right in front of us and I don’t want to do that.” - Terry Francona after his team’s win against the LA Angels in their game on Monday.
“He’s still a young guy. He’s progressed from being quick to the big leagues in the bullpen, to now back in the big leagues as a starter. He gave us four good innings the other day, gave us five today. He battled through the ups and downs. He mixed and matched, he used his stuff. He’s gonna get innings, so we’re gonna keep seeing him.” - Ray Montgomery after his team’s loss against the Reds in their game on Monday.
Starting Lineups
Cincinnati Reds
TJ Friedl (L) CF
Gavin Lux (L) DH
Elly De La Cruz (S) SS
Austin Hays (R) LF
Noelvi Marte (R) RF
Spencer Steer (R) 1B
Jose Trevino (R) C
Ke'Bryan Hayes (R) 3B
Matt McLain (R) 2B
Los Angeles Angels
Zach Neto (R) SS
Nolan Schanuel (L) 1B
Mike Trout (R) DH
Taylor Ward (R) LF
Yoán Moncada (S) 3B
Jo Adell (R) RF
Christian Moore (R) 2B
Logan O'Hoppe (R) C
Bryce Teodosio (R) CF
Statistical Leaders
Cincinnati Reds
Batting Average: Austin Wynns (.400)
Hits: Elly De La Cruz (134)
Home Runs: Elly De La Cruz (19)
RBI: Elly De La Cruz (76)
Stolen Bases: Elly De La Cruz (31)
Wins: Brady Singer (11)
Saves: Emilio Pagán (25)
ERA: Andrew Abbott (2.28)
Los Angeles Angels
Batting Average: Nolan Schanuel (.272)
Hits: Nolan Schanuel (123)
Home Runs: Taylor Ward (29)
RBI: Taylor Ward (91)
Stolen Bases: Zach Neto (22)
Wins: José Soriano (8)
Saves: Kenley Jansen (23)
ERA: Robert Stephenson (0.00)
Managers:
Cincinnati Reds: Terry Francona (1st season)
Los Angeles Angels: Ray Montgomery (Interim)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
