Cincinnati Reds vs Los Angeles Angels Prediction, Preview and Odds - 08/19/2025

by Rod Pearson

Monday, Aug 18, 2025
Game Time: 9:38 pm ET, Tuesday, August 19, 2025
Venue:  Angel Stadium, Anaheim, CA 
Where to Watch:  FDSOH, FDSW


Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Reds -137, Angels +112; Over/Under:  8.5 runs
Bet365:  Moneyline odds:  Reds -135, Angels +115; Over/Under:  8.5 runs
BetMGM:  Moneyline odds:  Reds -135, Angels +115; Over/Under:  8.5 runs

Season Record

Cincinnati Reds:  65-60 (3rd place, NL Central)
Los Angeles Angels:  60-64 (4th place, AL West)

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Recent Form
Cincinnati Reds:  5-5 last 10
Los Angeles Angels:  5-5 last 10



Cincinnati Reds vs Los Angeles Angels Preview and Analysis


The Reds are entering this series off a win and lost their 3-game series against the Milwaukee Brewers 2-1 in their last series. They enter this game with a 65-60 record overall and have a road record of 29-31. This is the 2nd game of a 3-game series with the Angels on Tuesday with the series opener still to be played on Monday. Their offense ranks 19th in the MLB with a .708 OPS. Brady Singer is their starting pitcher on Monday while Hunter Greene is making his start in this game on Tuesday. He is 5-3 with a 2.47 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 0 ER, 0 HR, and 0 BB with 6 SO on 3 hits through 6 IP against the Philadelphia Phillies.

The Angels are entering this series off a win and lost their 3-game series against the Athletics 2-1 in their last series. They enter this game with a 60-64 record overall and have a home record of 33-30. This is the 2nd game of a 3-game series with the Reds on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 14th in the MLB with a .714 OPS. Víctor Mederos is their starting pitcher on Monday while Kyle Hendricks is making his start in this game on Tuesday. He is 6-8 with a 4.88 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 5 earned runs, 1 homer, and 3 walks with 4 strikeouts on 6 hits through 3.1 innings pitched against the Los Angeles Dodgers.


Reds vs Angels Prediction

The current betting odds have the Reds listed as a favorite in this game according to Draftkings Sportsbook. The Reds have looked good in their games this season with their 65-60 record overall which has them right in the middle of the NL Central and in the Wild Card race. They haven't been a great road team though with their 29-31 road record. Meanwhile, the Angels haven't looked good in their games this season with their 60-64 record overall which has them right near the bottom of the AL West. They have looked better in their own ballpark though with their 33-30 home record this year. The Angels have been really up and down this season though while the Reds have managed to keep themselves in the playoff race all year, and now the Reds are going to have the better pitching matchup to take advantage of in this one. Greene is on the mound for the Reds in this one and he has looked good this season. He is 5-3 with a 2.47 ERA and hasn't been giving up many runs all year. He is coming off another great start in which he gave up no runs and the team has been having success with him lately too, winning 2 games in a row now with him starting. The Angels are going with Hendricks in this one and he hasn't looked great this season. He is 6-8 with a 4.88 ERA and he has been giving up quite a few runs all year. He is coming off another bad start in which he gave up 5 earned runs and the team has lost 2 of their last 3 games with him starting too. The Reds haven't looked their best lately, but they did just play a series against the hottest team in the MLB, and they will have some momentum in this series after ending that long win streak that the Brewers were on. The best way to place a bet here is on the Reds to win this game. 

Reds Angels Prediction:  Our MLB Pick for Tuesday, August 19, 2025 (9:38 pm ET start time) is Reds 6 Angels 3.
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MLB Betting Trends


Cincinnati Reds: 23-15 (+10.2 units) on the moneyline against AL West opponents. 223-225 (+12.3 units) on the moneyline in all games. 111-111 (+25.6 units) on the moneyline in road games. 34-22 OVER on the road when the total is 9 to 9.5.

Los Angeles Angels: 196-252 (-24.2 units) on the moneyline in all games. 103-122 (-21.8 units) on the moneyline in home games. 76-101 (-24.8 units) on the moneyline when the money line is +125 to -125. 29-13 OVER when the money line is +125 to -125.

Key Injuries


Cincinnati Reds:  C. Burns (SP) Fifteen Day IL - Elbow. N. Lodolo (SP) Fifteen Day IL - Finger. W. Miley (SP) Sixty Day IL - Flexor. I. Gibaut (RP) Fifteen Day IL - Shoulder. R. Lowder (SP) Sixty Day IL - Forearm. C. Spiers (RP) Sixty Day IL - Shoulder. T. Callihan (LF) Sixty Day IL - Forearm. B. Williamson (SP) Sixty Day IL - Elbow. J. Aguiar (SP) Sixty Day IL - Elbow.

Los Angeles Angels:  G. Campero (RF) Ten Day IL - Ankle. C. Taylor (CF) Ten Day IL - Hand. J. Soler (RF) Ten Day IL - Back. R. Stephenson (RP) Sixty Day IL - Bicep. H. Strickland (RP) Sixty Day IL - Shoulder. B. Joyce (RP) Sixty Day IL - Shoulder. A. Rendon (3B) Sixty Day IL - Hip.


Notable Quotes


“Oh, you don’t want to know [what I was thinking in the ninth]. The whole series was like [that]. I don’t know if I have years left, but whatever I have, it took some off.” - Terry Francona after his team’s win against the Brewers in their game on Sunday.


"I think collectively as a group, when you do stuff like that, from big ball, small ball, the bunt, the homer or the triple, the big hits, the baserunning, literally a piece of everything, it's fun to watch. That’s what we preach from Day 1 of Spring Training, and we did it all in one inning.” - Ray Montgomery after his team’s win against the A’s in their game on Sunday.


Starting Lineups


Cincinnati Reds
TJ Friedl (L) CF
Spencer Steer (R) 1B
Elly De La Cruz (S) SS
Miguel Andujar (R) LF
Austin Hays (R) DH
Noelvi Marte (R) RF
Jose Trevino (R) C
Ke'Bryan Hayes (R) 3B
Santiago Espinal (R) 2B

Los Angeles Angels
Zach Neto (R) SS
Nolan Schanuel (L) 1B
Mike Trout (R) DH
Taylor Ward (R) LF
Jo Adell (R) RF
Logan O'Hoppe (R) C
Christian Moore (R) 2B
Oswald Peraza (R) 3B
Bryce Teodosio (R) CF

Statistical Leaders


Cincinnati Reds
Batting Average:  Austin Wynns (.400)
Hits:  Elly De La Cruz (133)
Home Runs:  Elly De La Cruz (19)
RBI:  Elly De La Cruz (76)
Stolen Bases:  Elly De La Cruz (31)
Wins:  Nick Martinez (10)
Saves:  Emilio Pagán (25)
ERA:  Andrew Abbott (2.28)

Los Angeles Angels
Batting Average:  Bryce Teodosio (.270)
Hits:  Nolan Schanuel (121)
Home Runs:  Taylor Ward (29)
RBI:  Taylor Ward (90)
Stolen Bases:  Zach Neto (21)
Wins:  José Soriano (8)
Saves:  Kenley Jansen (23)
ERA:  Robert Stephenson (0.00)

Managers:
Cincinnati Reds: Terry Francona (1st season)
Los Angeles Angels: Ray Montgomery (Interim)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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