Cincinnati Bengals vs Cleveland Browns Prediction, Preview and Odds - 09/07/2025

Game Time: 1:00 pm ET, Sunday, September 7, 2025

Venue:  Huntington Bank Field, Cleveland, OH

Where to Watch:  FOX

DraftKings:  Point Spread:  Bengals -6, Browns +6; Over/Under:  47.5 points

Bet365:  Point Spread:  Bengals -6, Browns +6; Over/Under:  47.5 points

BetMGM:  Point Spread:  Bengals -6, Browns +6; Over/Under:  47.5 points

Cincinnati Bengals:  0-0 (AFC North)

Cleveland Browns:  0-0 (AFC North)

Do not miss out on our expert handicapper analysis! Jim Feist is on a HOT STREAK in the NFL on a 105-87-3 NFL RUN for +$7,960 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Cincinnati Bengals:  N/A

Cleveland Browns:  N/A

The Bengals finished last season with a 9-8 record overall and they were 3-3 in their division games too. They had a 3-5 record in their home games and had a 6-3 record in their road games where they will be in this game. Last season, their offense was averaging 27.8 points per game and their defense was allowing an average of 25.5 points per game. Their offense was also averaging 365.5 yards per game and their defense was allowing an average of 348.3 yards per game. Joe Burrow led the team in passing yards with 4,918, Chase Brown led the team in rushing yards with 990, and Ja'Marr Chase led the team in receiving yards with 1,708.

The Browns finished last season with a 3-14 record overall and they were 2-4 in their division games too. They had a 2-6 record in their home games and had a 1-8 record in their road games where they will be in this game. Last season, their offense was averaging 15.2 points per game and their defense was allowing an average of 25.6 points per game. Their offense was also averaging 300.8 yards per game and their defense was allowing an average of 342.1 yards per game. Jameis Winston led the team in passing yards with 2,121, Jerome Ford led the team in rushing yards with 565, and Jerry Jeudy led the team in receiving yards with 1,229.

The current betting odds have the Browns listed as a 6 point underdog in this game according to Draftkings Sportsbook. The Browns had a terrible season last year, finishing 3-14 overall and they were one of the worst teams in the NFL. Their season was plagued by QB injuries, but their QB room is in much better shape coming into this season. They have 2 promising rookies looking to prove themselves if they get a shot, and they have a solid veteran in Joe Flacco starting in this game. Flacco didn't have a great season last year, but he took this Browns team to the playoffs 2 seasons ago so he is familiar with this offense and should be able to plug right back in. Their defense wasn't great last season, but a lot of that was because they were always on the field with the offense unable to stay on the field and give them some rest. This will be a more competent offense with Flacco leading the charge and the defense should show improvement with the talent they have. Meanwhile, the Bengals didn't have a great season either by their standards. They had a winning 9-8 record overall, but they still missed the playoffs with one of the worst defenses in the NFL. It is tough to see this defense improving much this season either so the Browns will get their opportunities to put up points in this home opener. The Bengals still have a great offense with a ton of talent, but that didn't help much last season so even if they win this game, their defense will keep the Browns in it. The best way to place a bet here is on the Browns to cover the spread in this game. 

Bengals Browns Prediction:  Our NFL Pick for Sunday, September 7, 2025 (1:00 pm ET start time) is Bengals 27 Browns 24.

Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Cincinnati Bengals Cleveland Browns prediction, be sure to drop by every day for our weekly NFL predictions and previews.

Cincinnati Bengals: 6-3 ATS as a road favorite. 8-3 ATS as a favorite of 3.5 to 9.5 points. 16-10 UNDER on the road as a favorite of 3.5 to 9.5 points.

Cleveland Browns: 2-5 ATS as a home underdog of 7 points or less. 2-6 ATS in all games where the total is between 42.5 and 49 points. 11-6 UNDER in home games. 6-1 UNDER as a home underdog of 7 points or less. 

Cincinnati Bengals:  None.

Cleveland Browns:  None.

"Really hard decision. You know, both those guys, I thought, performed their best all training camp. And that's what I told Cal, is this wasn't a matter of somebody losing the competition. You know, it was, we got the best out of both those guys. Ultimately, we decided to go with Will, but I thought Cal had a really strong camp as well. And you know, there's a chance he ends up somewhere else, I'm sure." - Zac Taylor on the roster cuts.

"Got a strong offer for Kenny. Kenny’s a guy I think very highly of, and so do they. So, I wish him well. He’s a great person. He’s a really good football player, but those are the type of decisions that you have to make." - Kevin Stefanski on the team trading away Kenny Pickett.

WR Chase, Ja'Marr

WR Higgins, Tee

WR Iosivas, Andrei

TE Gesicki, Mike

QB Burrow, Joe

RB Brown, Chase

WR Tillman, Cedric

WR Jeudy, Jerry

WR Thrash, Jamari

TE Njoku, David

QB Flacco, Joe

RB Ford, Jerome

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Coaches:

Cincinnati Bengals: Zac Taylor (7th season)

Cleveland Browns: Kevin Stefanski (6th season)