Cincinnati Bearcats vs Oklahoma State Cowboys Prediction, Picks and Game Preview - 10/18/2025

by Rod Pearson

Thursday, Oct 16, 2025
Game Time: 8:00 pm ET, Saturday, October 18, 2025
Venue:  Boone Pickens Stadium, Stillwater, OK
Where to Watch:  ESPN2


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Cincinnati -21.5, OK State +21.5; Over/Under:  57.5 points
Bet365:  Point Spread:  Cincinnati -21.5, OK State +21.5; Over/Under:  57.5 points
BetMGM:  Point Spread:  Cincinnati -21.5, OK State +21.5; Over/Under:  57.5 points

Season Record

Cincinnati Bearcats:  5-1 (3-0) (3rd place, Big 12)
Oklahoma State Cowboys:  1-5 (0-3) (16th place, Big 12)

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Recent Form
Cincinnati Bearcats:  won their last game at home against the Central Florida Knights 20-11.
Oklahoma State Cowboys:  lost their last game at home against the Houston Cougars 39-17.


Cincinnati Bearcats vs Oklahoma State Cowboys Preview and Analysis


Cincinnati is entering this game with a 5-1 record overall and they have a 3-0 record in their conference games too. They are 4-0 in their home games, 1-0 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They won their last game against UCF 20-11. Brendan Sorsby was the starting QB and he completed 12/21 passes for 191 passing yards, 2 touchdowns, and 0 interceptions. Evan Pryor led the team in rushing yards with 48. Joe Royer led the receivers with 83 receiving yards on 2 receptions. Jonathan Thompson led the defense in that game with 4 solo tackles and 4 assisted tackles while Isaiah Rogers led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
 
 
 
Oklahoma State is entering this game with a 1-5 record overall and they have a 0-3 record in their conference games too. They are 1-3 in their home games, 0-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against Houston 39-17. Sam Jackson V was the starting QB and he completed 7/16 passes for 84 passing yards, 0 touchdowns, and 1 interception. Rodney Fields Jr. led the team in rushing yards with 44. Rodney Fields Jr. led the receivers with 63 receiving yards on 2 receptions and 1 TD. Mordecai McDaniel led the defense in that game with 10 solo tackles and 3 assisted tackles while Malik Charles led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.


Cincinnati vs Oklahoma State Prediction

The current betting odds have Cincinnati listed as a 21.5 point favorite in this game according to Draftkings Sportsbook. Cincinnati has looked great in their games this season with their 5-1 record overall and their 3-0 conference record which has them right near the top of the Big 12. Their only loss this season was against Nebraska at the beginning of the year, but they have looked a lot better since that loss and their offense has been putting up a ton of points. They are off a 20-11 win over UCF in their last one and they did struggle in that game, but they will be looking to get right with a better game and they are facing one of the worst teams in the Big 12 here. Meanwhile, Oklahoma State has looked terrible in their games this season with their 1-5 record overall and their 0-3 conference record which has them right near the bottom of the Big 12. They are off a 39-17 loss against Houston in their last one and they have been getting blown out in most of their games this season. Their offense hasn't looked good at all and their defense has looked terrible, giving up a ton of points in every game. Oklahoma State is a disaster at the moment and they have already fired their head coach too. Cincinnati has a really good offense that is going to put up a ton of points on this defense while Oklahoma State continues to struggle offensively. The best way to place a bet here is on Cincinnati to cover the spread in this game. 

Cincinnati Oklahoma State Prediction:  Our NCAAF Pick for Saturday, October 18, 2025 (8:00 pm ET start time) is Cincinnati 49 OK State 13.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Cincinnati Bearcats Oklahoma State Cowboys prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.

NCAAF Betting Trends


Cincinnati Bearcats: 30-20 ATS after a 2 game home stand. 36-27 ATS vs. poor passing defenses - allowing 250 or more passing yards/game. 7-4 OVER in road lined games. 4-1 OVER after allowing 14 points or less last game. 4-0 OVER vs. poor passing defenses - allowing 8 or more passing yards/att.

Oklahoma State Cowboys: 12-20 ATS in all lined games. 6-11 ATS as an underdog. 3-9 ATS after allowing 37 points or more last game. 4-9 ATS off a loss against a conference rival. 12-5 OVER as an underdog. 14-8 OVER against conference opponents.

Key Injuries


Cincinnati Bearcats:  D. Logan (DL) Out - Undisclosed. R. Casanova (LB) Out - Undisclosed. Q. Staten (LB) Out - Undisclosed. C. Roetherford (DL) Out - Undisclosed. T. Holcomb (LB) Out - Undisclosed. K. Woodburn (WR) Out - Undisclosed.

Oklahoma State Cowboys:  D. Thomas (LB) Out - Undisclosed. D. Smith (S) Out - Undisclosed. M. Samuel (OG) Out - Undisclosed. J. Oliphant Jr. (LB) Questionable - Undisclosed. N. McKinney (OG) Doubtful - Undisclosed. M. Lopez (WR) Out - Undisclosed. D. Lofton (WR) Out - Undisclosed. J. Johnson (CB) Probable - Undisclosed. J. Johnson (DL) Out - Undisclosed. D. Kabongo (S) Out - Undisclosed. J. Ford (TE) Out - Undisclosed. S. Freibaum (LS) Out - Undisclosed. H. Hejny (QB) Out - Foot. O. Hammond (TE) Out - Undisclosed. C. Epps (S) Out - Undisclosed. J. Davies (CB) Out - Undisclosed. D. Boykins (S) Out - Undisclosed. L. Canepa (OG) Out - Undisclosed. D. Brown (DL) Probable - Knee. Z. Flores (QB) Questionable - Undisclosed. T. Shettron (WR) Out - Knee.

Notable Quotes


“We defended a lot of snaps today and only gave up 11 points. We’ll take that. Our offense is not going to be complacent after that showing. It’s not good enough.” - Scott Satterfield after his team’s win against UCF in their last game. 


“Disappointed. Felt pretty good coming into this game. It's just kind of awkward or odd, like, we come out and hit some plays, move the ball ... there's a point in the game you say, ‘OK this is going to be the one', you know? And then, it’s kind of a collection of things that occur ... and then it just kind of spirals.” - Doug Meacham after his team’s loss against Houston in their last game. 


Starting Lineups


Cincinnati Bearcats
WR Caldwell, Jeff
WR Goodie, Caleb
WR Allen, Cyrus
TE Royer, Joe
QB Sorsby, Brendan
RB Pryor, Evan

Oklahoma State Cowboys
WR Davis, Terrill
WR Rigby, Shamar
WR Freeman, Gavin
TE Stewart, Quinton
QB Flores, Zane
RB Fields Jr., Rodney

Statistical Leaders


Cincinnati Bearcats
Passing: Brendan Sorsby (1,448)
Rushing: Evan Pryor (349)
Receiving: Caleb Goodie (354)
Touchdowns: Cyrus Allen (5)

Oklahoma State Cowboys
Passing: Zane Flores (696)
Rushing: Rodney Fields Jr. (257)
Receiving: Gavin Freeman (203)
Touchdowns: Trent Howland (2)

Coaches:
Cincinnati Bearcats: Scott Satterfield (3rd season)
Oklahoma State Cowboys: Doug Meacham (Interim)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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