Chicago White Sox vs Baltimore Orioles Prediction, Preview and Odds - 06/30/2026

Game Time: 6:35 pm ET, Tuesday, June 30, 2026

Venue:  Oriole Park at Camden Yards, Baltimore, MD 

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  White Sox +128, Orioles -155; Over/Under:  10.5 runs

Bet365:  Moneyline odds:  White Sox +125, Orioles -150; Over/Under:  10.5 runs

BetMGM:  Moneyline odds:  White Sox +125, Orioles -150; Over/Under:  10.5 runs

Chicago White Sox:  43-39 (1st place, AL Central)

Baltimore Orioles:  39-46 (4th place, AL East)

Do not miss out on our expert handicapper analysis! ASA, Inc. is on a HOT STREAK in MLB on a 22-10 MLB RUN for +$11,200 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Chicago White Sox:  5-5 last 10

Baltimore Orioles:  4-6 last 10

The White Sox are entering this series off a loss and won their 3-game series against the Kansas City Royals 2-1 in their last series. They enter this game with a 43-39 record overall and have a road record of 15-25. This is the 2nd game of a 3-game series with the Orioles on Tuesday with the series opener still to be played on Monday. Their offense ranks 6th in the MLB with a .738 OPS. Sean Burke is their starting pitcher on Monday while Erick Fedde is making his start in this game on Tuesday. He is 2-6 with a 4.34 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 1 ER, 0 HR, and 3 BB with 2 SO on 5 hits through 4 IP against the Cleveland Guardians.

The Orioles are entering this series off a loss and lost their 3-game series against the Washington Nationals 2-1 in their last series. They enter this game with a 39-46 record overall and have a home record of 23-21. This is the 2nd game of a 3-game series with the White Sox on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 15th in the MLB with a .718 OPS. Shane Baz is their starting pitcher on Monday while rookie pitcher Trey Gibson is making his start in this game on Tuesday. He is 1-2 with a 5.64 ERA this season. His team lost their last 4 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 1 homer, and 2 walks with 5 strikeouts on 3 hits through 4 innings pitched against the Los Angeles Angels.

The current betting odds have the White Sox listed as an underdog in this game according to Draftkings Sportsbook. The White Sox have looked good in their games this season with their 43-39 record overall which has them right at the top of the AL Central. They haven't been a good road team though with their 15-25 road record this year. Meanwhile, the Orioles haven't looked good in their games this season with their 39-46 record overall which has them right near the bottom of the AL East. They have looked better in their own ballpark though with their 23-21 home record this season. The Orioles have looked better at home while the White Sox have looked a lot worse in road games, but the Orioles are 4-6 in their last 10 games and haven't looked good lately. They are going with Gibson in this one and he hasn't looked great this season. He is 1-2 with a 5.64 ERA and he has had some trouble in his rookie year. He only gave up 2 earned runs in his last start, but that hasn't been a common theme for him and the team has been having trouble with him too, losing 4 games in a row now with him starting. The White Sox are going with Fedde in this one and he hasn't looked great this season either. He is 2-6 with a 4.34 ERA, but lately he has looked a lot better. His team has still lost 2 games in a row now with him starting, but he only gave up 1 earned run in his last start and he hasn't been giving up many runs in his starts lately. The White Sox also have the much better offense this season and they have been putting up a lot of runs lately, so look for them to take advantage of this pitching matchup. The best way to place a bet here is on the White Sox to win this game. 

White Sox Orioles Prediction:  Our MLB Pick for Tuesday, June 30, 2026 (6:35 pm ET start time) is White Sox 8 Orioles 5.

Don't miss our champion handicappers free picks, best bets, and expert baseball picks today.  And if you enjoyed this Chicago White Sox Baltimore Orioles prediction, be sure to drop by every day for our daily MLB projections and previews.

Chicago White Sox: 71-100 (+4.6 units) on the moneyline as an underdog of +125 to +175. 3-1 (+4 units) on the moneyline when the total is 10 to 10.5. 34-40 (+5.2 units) on the moneyline vs. a starting pitcher whose lasts less than 5 innings per start. 24-15 OVER in road games.

Baltimore Orioles: 205-206 (-24.5 units) on the moneyline in all games. 106-101 (-25.6 units) on the moneyline in home games. 118-105 (-30.9 units) on the moneyline as a favorite of -110 or higher. 11-6 OVER vs. a starting pitcher whose lasts less than 5 innings per start.

Chicago White Sox:  E. Pereira (RF) Seven Day IL - Concussion. T. Gilbert (RP) Fifteen Day IL - Shoulder. A. Hays (LF) Sixty Day IL - Calf. M. Murakami (1B) Ten Day IL - Hamstring. J. Leasure (RP) Sixty Day IL - Flexor. N. Schultz (SP) Fifteen Day IL - Knee. T. Murray (LF) Sixty Day IL - Shoulder. P. Berroa (RP) Sixty Day IL - Elbow. B. Baldwin (LF) Sixty Day IL - Elbow. M. Vasil (RP) Sixty Day IL - Elbow. D. Thorpe (SP) Sixty Day IL - Elbow. K. Bush (SP) Sixty Day IL - Elbow.

Baltimore Orioles:  C. Bassitt (SP) Fifteen Day IL - Back. D. Kremer (SP) Sixty Day IL - Quad. R. Mountcastle (1B) Sixty Day IL - Foot. Y. Hiraldo (RP) Sixty Day IL - Shoulder. Z. Eflin (SP) Sixty Day IL - Elbow. J. Westburg (3B) Sixty Day IL - UCL. F. Bautista (RP) Sixty Day IL - Shoulder. C. Selby (SP) Sixty Day IL - Shoulder.

“It was a tough day for Anthony. Thought there was not his best command. His stuff was OK, but not his best command. I thought a really nice job by the Royals with two-strike hitting, using the whole field, I thought they made it really tough on him.” - Will Venable after his team’s loss against the Royals in their game on Sunday. 

“Every loss is difficult, but yeah, these two [vs. Washington], for sure.” - Craig Albernaz after his team’s loss against the Nationals in their game on Sunday. 

Sam Antonacci (L) LF

Miguel Vargas (R) 3B

Kyle Teel (L) C

Andrew Benintendi (L) DH

Colson Montgomery (L) SS

Chase Meidroth (R) 2B

Braden Montgomery (S) RF

Tristan Peters (L) CF

Jacob Gonzalez (L) 1B

Taylor Ward (R) LF

Gunnar Henderson (L) SS

Adley Rutschman (S) C

Pete Alonso (R) DH

Samuel Basallo (L) 1B

Dylan Beavers (L) RF

Coby Mayo (R) 3B

Colton Cowser (L) CF

Jackson Holliday (L) 2B

Batting Average:  Randal Grichuk (.296)

Hits:  Chase Meidroth (83)

Home Runs:  Munetaka Murakami (20)

RBI:  Miguel Vargas (52)

Stolen Bases:  Luisangel Acuña (14)

Wins:  Davis Martin (9)

Saves:  Seranthony Domínguez (12)

ERA:  Duncan Davitt (0.00)

Batting Average:  Chadwick Tromp (.667)

Hits:  Taylor Ward (81)

Home Runs:  Pete Alonso (19)

RBI:  Pete Alonso (58)

Stolen Bases:  Leody Taveras (9)

Wins:  Brandon Young (6)

Saves:  Ryan Helsley (8)

ERA:  Jose Espada (0.00)

Managers:

Chicago White Sox: Will Venable (2nd season)

Baltimore Orioles: Craig Albernaz (1st season)