Chicago Cubs vs Toronto Blue Jays Prediction, Preview and Odds - 08/12/2025

Game Time: 7:07 pm ET, Tuesday, August 12, 2025

Venue:  Rogers Centre, Toronto, ON

Where to Watch:  TBS

DraftKings:  Moneyline odds:  Cubs +104, Blue Jays -126; Over/Under:  9 runs

Bet365:  Moneyline odds:  Cubs +105, Blue Jays -125; Over/Under:  9 runs

BetMGM:  Moneyline odds:  Cubs +105, Blue Jays -125; Over/Under:  9 runs

Chicago Cubs:  67-50 (2nd place, NL Central)

Toronto Blue Jays:  69-50 (1st place, AL East)

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Chicago Cubs:  5-5 last 10

Toronto Blue Jays:  6-4 last 10

The Cubs are entering this series off a loss and lost their 3-game series against the St Louis Cardinals 2-1 in their last series. They enter this game with a 67-50 record overall and have a road record of 31-28. This is the series opener of a 3-game series with the Blue Jays on Tuesday and they have Monday off as a day of rest. Their offense ranks 5th in the MLB with a .760 OPS. Shota Imanaga was their starting pitcher on Sunday while Ben Brown is making his start in this game on Tuesday. He is 5-7 with a 6.04 ERA this season. His team lost 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 ER, 0 HR, and 0 BB with 5 SO on 2 hits through 4 IP against the Cincinnati Reds.

The Blue Jays are entering this series off a win and lost their 3-game series against the Los Angeles Dodgers 2-1 in their last series. They enter this game with a 69-50 record overall and have a home record of 38-19. This is the 1st game of a 3-game series with the Cubs on Tuesday and they have Monday off as a day of rest. Their offense ranks 3rd in the MLB with a .767 OPS. Eric Lauer was their starting pitcher on Sunday while José Berríos is making his start in this game on Tuesday. He is 8-4 with a 3.89 ERA this season. His team won their last 4 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 3 earned runs, 1 homer, and 1 walk with 5 strikeouts on 7 hits through 5.1 innings pitched against the Colorado Rockies.

The current betting odds have the Blue Jays listed as a slight favorite in this game according to Draftkings Sportsbook. The Blue Jays have looked great in their games this season with their 69-50 record overall which has them right at the top of the AL East with one of the best records in the MLB. They have also looked great in their own ballpark this year with their 38-19 home record. Meanwhile, the Cubs have looked really good in their games this season with their 67-50 record overall which has them right near the top of the NL Central. They have been a good road team too with their 31-28 road record this season. The Blue Jays have been rolling in their games lately as they are 6-4 in their last 10 games while the Cubs are 5-5, and the Blue Jays also have the better pitching matchup to take advantage of at home. The Blue Jays are going with Berrios in this one and he has looked good this season. He is 8-4 with a 3.89 ERA and the team has been having a ton of success with him lately. He did give up 3 earned runs in his last start, but that hasn't been a common theme for him at home this year and the team has won 4 games in a row now with him starting too. The Cubs are going with Brown in this one and he hasn't looked good this season. He is 5-7 with a 6.04 ERA and has been giving up quite a few runs this year. He is coming off a good start in which he gave up 1 earned run, but that hasn't been a common theme for him and the Cubs have still lost 3 of their last 4 games with him starting. The Blue Jays can take advantage of this pitching matchup and they have looked a lot better in home games this year. The best way to place a bet here is on the Blue Jays to win this game. 

Cubs Blue Jays Prediction:  Our MLB Pick for Tuesday, August 12, 2025 (7:07 pm ET start time) is Blue Jays 6 Cubs 4.

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Chicago Cubs: 23-16 (+8 units) on the moneyline against AL East opponents. 234-207 (+10.2 units) on the moneyline in all games. 77-55 (+18.6 units) on the moneyline in an inter-league game. 23-14 UNDER against AL East opponents.

Toronto Blue Jays: 232-213 (-10.1 units) on the moneyline in all games. 120-99 (-11 units) on the moneyline in home games. 132-109 (-24.7 units) on the moneyline as a favorite of -110 or higher. 26-19 UNDER at home when the total is 9 to 9.5.

Chicago Cubs:  M. Soroka (SP) Fifteen Day IL - Shoulder. M. Amaya (C) Sixty Day IL - Oblique. J. Taillon (SP) Fifteen Day IL - Calf. E. Morgan (RP) Sixty Day IL - Elbow. J. Assad (RP) Sixty Day IL - Oblique. J. Steele (SP) Sixty Day IL - Elbow.

Toronto Blue Jays:  G. Springer (RF) Seven Day IL - Head. B. Francis (SP) Sixty Day IL - Shoulder. R. Burr (RP) Sixty Day IL - Shoulder. N. Sandlin (RP) Fifteen Day IL - Elbow. A. Gimenez (2B) Ten Day IL - Ankle. Y. Garcia (RP) Fifteen Day IL - Ankle. A. Santander (RF) Sixty Day IL - Shoulder. S. Bieber (SP) Sixty Day IL - Elbow. A. Manoah (SP) Sixty Day IL - Elbow. A. Bastardo (SP) Sixty Day IL - Elbow.

“We didn’t create enough scoring opportunities.” - Craig Counsell after his team’s loss against the Cardinals in their game on Sunday.

“It’s a great effort right there from everybody -- really everybody. I think we used everybody except Tommy [Nance] and Buddy [Kennedy] today, so it’s what we can do. When we play our kind of game, we can beat and play with anyone.” - John Schneider after his team’s win against the LA Dodgers in their game on Sunday.

Michael Busch (L) 1B

Seiya Suzuki (R) DH

Kyle Tucker (L) RF

Carson Kelly (R) C

Pete Crow-Armstrong (L) CF

Ian Happ (S) LF

Nico Hoerner (R) 2B

Dansby Swanson (R) SS

Matt Shaw (R) 3B

Nathan Lukes (L) RF

Bo Bichette (R) SS

Vladimir Guerrero Jr. (R) 1B

Addison Barger (L) 3B

Ty France (R) DH

Daulton Varsho (L) CF

Ernie Clement (R) 2B

Joey Loperfido (L) LF

Tyler Heineman (S) C

Batting Average:  Nico Hoerner (.291)

Hits:  Nico Hoerner (125)

Home Runs:  Pete Crow-Armstrong (27)

RBI:  Seiya Suzuki (84)

Stolen Bases:  Pete Crow-Armstrong (30)

Wins:  Matthew Boyd (11)

Saves:  Daniel Palencia (15)

ERA:  Michael Fulmer (0.00)

Batting Average:  Joey Loperfido (.382)

Hits:  Bo Bichette (147)

Home Runs:  Vladimir Guerrero (19)

RBI:  Bo Bichette (78)

Stolen Bases:  George Springer (12)

Wins:  Chris Bassitt (11)

Saves:  Jeff Hoffman (26)

ERA:  Ryan Burr (0.00)

Managers:

Chicago Cubs: Craig Counsell (2nd season)

Toronto Blue Jays: John Schneider (4th season)