Charlotte Hornets vs Philadelphia 76ers Prediction, Preview and Odds - 10/25/2025

Game Time: 7:30 pm ET, Saturday, October 25, 2025

Venue:  Xfinity Mobile Arena, Philadelphia, PA

Where to Watch:  FDSSE-CHA, NBCS-P

DraftKings:  Point Spread:  Hornets +5.5, 76ers -5.5; Over/Under:  231.5 points

Bet365:  Point Spread:  Hornets +5.5, 76ers -5.5; Over/Under:  231.5 points

BetMGM:  Point Spread:  Hornets +5.5, 76ers -5.5; Over/Under:  232.5 points

Charlotte Hornets:  1-0 (2nd place, Southeast Division)

Philadelphia 76ers:  1-0 (3rd place, Atlantic Division)

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Charlotte Hornets:  1-0 last 1

Philadelphia 76ers:  1-0 last 1

The Hornets are entering this game with a 1-0 record overall this season and they are 0-0 in their road games this season where they will be in this game. They are entering this game off a win against the Brooklyn Nets. Brandon Miller led the team in points in that game with 25 while LaMelo Ball was next on the team with 20 points. LaMelo Ball led the team in assists in that game with 8 while Miles Bridges and Ryan Kalkbrenner each led the team in rebounds with 11. They were 53.3% from the field, 47.2% from 3-point range, and 69.7% from the free throw line with their shots in that game. Their offense is averaging 136 PPG and their defense is allowing their opponents to average 117 PPG against them. The Hornets have an ATS record of 1-0 this season and their O/U record is 1-0.

The 76ers are entering this game with a 1-0 record overall this season and they are 0-0 in their home games this season where they will be in this game. They are entering this game off a win against the Boston Celtics. Tyrese Maxey led the team in points in that game with 40 while V. J. Edgecombe was next on the team with 34 points. Tyrese Maxey led the team in assists in that game with 6 while V. J. Edgecombe led the team in rebounds with 7. They were 45.9% from the field, 39% from 3-point range, and 76.7% from the free throw line with their shots in that game. Their offense is averaging 117 PPG and their defense is allowing their opponents to average 116 PPG against them. The 76ers have an ATS record of 1-0 this season and their O/U record is 1-0.

The current betting odds have the 76ers listed as a 5.5 point favorite in this game according to Draftkings Sportsbook. The Hornets have a 1-0 record overall this season after winning their season opener over the Nets. They looked great in that one with a 136-117 win at home and they have a lot of young players that can turn this team around. They have been one of the worst teams in the NBA over the last few seasons, but that opening win still isn't that impressive since the Nets are also one of the worst teams in the league. Meanwhile, the 76ers have a 1-0 record overall this year and they are off a tough win on the road against the Celtics. They fought hard to win a tight game 117-116, but they should play a lot better in this game. Now they are back at home against a weaker opponent and this is their home opener so they are going to bring their best effort. They won on the road in Boston with Embiid not having a great game too so look for him to step up here at home. The 76ers have a lot of talent this season and their 1st round draft pick VJ Edgecomb is only going to add to that. The Hornets looked good in their home opener, but this is a different animal going on the road against an improved 76ers team and the Hornets are going to look more like the team from last season in this one. The best way to place a bet here is on the 76ers to cover the spread in this game. 

Hornets 76ers Prediction:  Our NBA Pick for Saturday, October 25, 2025 (7:30 pm ET start time) is 76ers 124 Hornets 116.

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Charlotte Hornets: Will be posted by 12:00pm ET, 10/25/2025.

Philadelphia 76ers: Will be posted by 12:00pm ET, 10/25/2025.

Charlotte Hornets:  J. Green (SG) Day To Day - Shoulder. G. Williams (PF) Day To Day - ACL.

Philadelphia 76ers:  T. Watford (PF) Day To Day - Hamstring. P. George (PF) Day To Day - Knee. J. McCain (SG) Out - Thumb.

“The crowd was lit, as I was expecting. It was fun to be in the Spectrum, and it was fun to just have another opportunity to play a game and try to build some good habits on both sides of the ball. I think defensively, we did a lot of really good things and things that we’ll continue to try to emphasize. There are some areas where we can get better. We had a 37-point third quarter, and the second quarter, you feel like you put them in the bonus kind of early, so as good as I thought we were, we can get better. And then offensively, I loved the pace that we were pretty much able to sustain, the ball movement was great, and the first half, we had five turnovers, so we were taking care of the ball.” - Charles Lee after his team’s win against the Nets in their game on Wednesday.

“I’m super happy he was out there. I think that he played good. I know that’s going to sound silly, one for nine. He just didn’t shoot it very good.” - Nick Nurse on Joel Embiid after his team’s win against the Celtics in their game on Wednesday.

PG LaMelo Ball

SG Brandon Miller

SF Kon Knueppel

PF Miles Bridges

C Ryan Kalkbrenner

PG Tyrese Maxey

SG VJ Edgecombe

SF Kelly Oubre Jr.

PF Dominick Barlow

C Joel Embiid

PPG: Brandon Miller (25)

APG: LaMelo Ball (8)

Reb/G: Miles Bridges (11)

PPG: Tyrese Maxey (40)

APG: Tyrese Maxey (6)

Reb/G: Dominick Barlow (8)

Coaches:

Charlotte Hornets: Charles Lee (2nd season)

Philadelphia 76ers: Nick Nurse (3rd season)