Boston Red Sox vs New York Yankees Prediction, Preview and Odds - 08/23/2025

by Rod Pearson

Friday, Aug 22, 2025
Game Time: 1:05 pm ET, Saturday, August 23, 2025
Venue:  Yankee Stadium, Bronx, NY
Where to Watch:  MLBN


Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Red Sox -137, Yankees +112; Over/Under:  8.5 runs
Bet365:  Moneyline odds:  Red Sox -130, Yankees +110; Over/Under:  8.5 runs
BetMGM:  Moneyline odds:  Red Sox -130, Yankees +110; Over/Under:  8.5 runs

Season Record

Boston Red Sox:  69-59 (3rd place, AL East)
New York Yankees:  69-58 (2nd place, AL East)

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Recent Form
Boston Red Sox:  4-6 last 10
New York Yankees:  7-3 last 10



Boston Red Sox vs New York Yankees Preview and Analysis


The Red Sox are entering this series off a loss and got swept in their 2-game series against the Baltimore Orioles 2-0 in their last series. They enter this game with a 69-59 record overall and have a road record of 28-34. This is the 3rd game of a 4-game series with the Yankees on Saturday with the 2nd game still to be played on Friday. The Red Sox won the series opener on Thursday. Their offense ranks 7th in the MLB with a .749 OPS. Brayan Bello is their starting pitcher on Friday while Garrett Crochet is making his start in this game on Saturday. He is 13-5 with a 2.43 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 ER, 1 HR, and 1 BB with 8 SO on 3 hits through 7 IP against the Miami Marlins.

The Yankees are entering this series off a win and completed the sweep in their 2-game series against the Tampa Bay Rays 2-0. They enter this game with a 69-58 record overall and have a home record of 37-26. This is the 3rd game of a 4-game series with the Red Sox on Saturday with the 2nd game of this series still to be played on Friday. The Yankees lost the 1st game of this series on Thursday. Their offense ranks 1st in the MLB with a .784 OPS. Max Fried is their starting pitcher on Friday while Will Warren is making his start in this game on Saturday. He is 7-5 with a 4.25 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 1 walk with 3 strikeouts on 6 hits through 4.2 innings pitched against the St Louis Cardinals.


Red Sox vs Yankees Prediction

The current betting odds have the Red Sox listed as a favorite in this game according to Draftkings Sportsbook. The Red Sox have looked good in their games this season with their 69-59 record overall which has them right in the middle of the AL East. They haven't been a great road team though with their 28-34 road record this year. Meanwhile, the Yankees have looked good in their games this season with their 69-58 record overall which has them right near the top of the AL East. They have also looked great in their own ballpark this year with their 37-26 home record. The Yankees have been red hot lately as they are 7-3 in their last 10 games while the Red Sox are only 4-6, but the Red Sox did take the 1st game of this series on Thursday and they have the better pitching matchup to take advantage of in this one. The Red Sox are going with Crochet in this one and he has looked great this season. He is 13-5 with a 2.43 ERA and he has been their ace. His team has lost 2 games in a row now with him starting, but that hasn't been a common theme this year and he is coming off another good start in which he gave up 1 earned run. The Yankees are going with Warren in this one and he hasn't looked great this season. He is 7-5 with a 4.25 ERA and has been giving up quite a few runs in his starts. His team has won 2 games in a row now with him starting and he is coming off a good start in which he gave up 1 earned run, but that hasn't been a common theme for him this year and he isn't going to have another great start against one of the best offenses in the MLB. The Red Sox also need to win this series to get ahead of the Yankees in the AL East so they will bring their best effort for Crochet. The best way to place a bet here is on the Red Sox to win this game. 

Red Sox Yankees Prediction:  Our MLB Pick for Saturday, August 23, 2025 (1:05 pm ET start time) is Red Sox 6 Yankees 2.
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MLB Betting Trends


Boston Red Sox: 110-114 (+4.3 units) on the moneyline in road games. 57-52 (+10.4 units) on the moneyline on the road when the total is 8 to 8.5. 167-161 (+9.2 units) on the moneyline vs. a team with a good bullpen whose WHIP is 1.350 or better. 41-26 OVER on the road with a money line of -100 to -150.

New York Yankees: 252-212 (-29.8 units) on the moneyline in all games. 127-105 (-29.7 units) on the moneyline in home games. 82-93 (-16.4 units) on the moneyline when the money line is +125 to -125. 32-18 OVER at home when the money line is +125 to -125.

Key Injuries


Boston Red Sox:  W. Abreu (RF) Ten Day - Calf. R. Refsnyder (RF) Ten Day IL - Oblique. L. Guerrero (RP) Sixty Day IL - Elbow. T. Houck (SP) Sixty Day IL - Flexor. H. Dobbins (SP) Sixty Day IL - ACL. M. Mayer (3B) Ten Day IL - Wrist. L. Hendriks (RP) Sixty Day IL - Hip. J. Slaten (RP) Sixty Day IL - Shoulder. J. Winckowski (RP) Sixty Day IL - Elbow. T. Casas (1B) Sixty Day IL - Knee. K. Crawford (SP) Sixty Day IL - Knee. P. Sandoval (SP) Sixty Day IL - Elbow.

New York Yankees:  B. Headrick (RP) Fifteen Day IL - Forearm. A. Slater (LF) Ten Day IL - Hamstring. J. Loaisiga (RP) Fifteen Day IL - Back. C. Schmidt (SP) Sixty Day IL - Forearm. F. Cruz (RP) Fifteen Day IL - Oblique. R. Yarbrough (SP) Fifteen Day IL - Oblique. O. Cabrera (3B) Sixty Day IL - Ankle. J. Cousins (RP) Sixty Day IL - Elbow. G. Cole (SP) Sixty Day IL - Elbow.


Notable Quotes


"It’s the ability of not swinging at balls that gives you confidence. He's always in control. He works hard every single day. This kid, he wants to be the best out there. Today, we needed everything from him.” - Alex Cora after his team’s win against the Yankees in their game on Thursday.


"Just not a real clean game. Not a great night for us.” - Aaron Boone after his team’s loss against the Red Sox in their game on Thursday.


Starting Lineups


Boston Red Sox
Roman Anthony (L) RF
Alex Bregman (R) 3B
Jarren Duran (L) LF
Trevor Story (R) SS
Nathaniel Lowe (L) 1B
Masataka Yoshida (L) DH
Ceddanne Rafaela (R) CF
David Hamilton (L) 2B
Carlos Narváez (R) C

New York Yankees
Trent Grisham (L) CF
Aaron Judge (R) DH
Cody Bellinger (L) LF
Giancarlo Stanton (R) RF
Ben Rice (L) C
Jazz Chisholm Jr. (L) 2B
Paul Goldschmidt (R) 1B
Ryan McMahon (L) 3B
Anthony Volpe (R) SS

Statistical Leaders


Boston Red Sox
Batting Average:  Alex Bregman (.303)
Hits:  Jarren Duran (130)
Home Runs:  Wilyer Abreu (22)
RBI:  Trevor Story (79)
Stolen Bases:  Trevor Story (22)
Wins:  Garrett Crochet (13)
Saves:  Aroldis Chapman (23)
ERA:  Nick Burdi (0.00)

New York Yankees
Batting Average:  Amed Rosario (.500)
Hits:  Aaron Judge (140)
Home Runs:  Aaron Judge (40)
RBI:  Aaron Judge (92)
Stolen Bases:  Jazz Chisholm (22)
Wins:  Max Fried (13)
Saves:  Devin Williams (18)
ERA:  Adam Ottavino (0.00)

Managers:
Boston Red Sox: Álex Cora (5th season)
New York Yankees: Aaron Boone (8th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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