Boston Celtics vs New York Knicks Prediction, Preview and Odds - 10/24/2025

 

Game Time: 7:30 pm ET, Friday, October 24, 2025

Venue:  Madison Square Garden, New York, NY 

Where to Watch:  Prime Video

DraftKings:  Point Spread:  Celtics +6.5, Knicks -6.5; Over/Under:  227.5 points

Bet365:  Point Spread:  Celtics +6.5, Knicks -6.5; Over/Under:  227.5 points

BetMGM:  Point Spread:  Celtics +6.5, Knicks -6.5; Over/Under:  227.5 points

Boston Celtics:  0-1 (4th place, Atlantic Division)

New York Knicks:  1-0 (2nd place, Atlantic Division)

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Boston Celtics:  0-1 last 10

New York Knicks:  1-0 last 10

The Celtics are entering this game with a 0-1 record overall this season and they are 0-0 in their road games this season where they will be in this game. They are entering this game off a loss against the Philadelphia 76ers. Jaylen Brown and Derrick White each led the team in points in that game with 25 while Neemias Queta was next on the team with 17 points. Jaylen Brown and Derrick White each led the team in assists in that game with 4 while Neemias Queta led the team in rebounds with 8. They were 45.1% from the field, 25.6% from 3-point range, and 88.5% from the free throw line with their shots in that game. Their offense is averaging 116 PPG and their defense is allowing their opponents to average 117 PPG against them. The Celtics have an ATS record of 0-1 this season and their O/U record is 1-0.

The Knicks are entering this game with a 1-0 record overall this season and they are 1-0 in their home games this season where they will be in this game. They are entering this game off a win against the Cleveland Cavaliers. OG Anunoby led the team in points in that game with 24 while Jalen Brunson was next on the team with 23 points. Mikal Bridges led the team in assists in that game with 6 while OG Anunoby led the team in rebounds with 14. They were 43% from the field, 35% from 3-point range, and 86.1% from the free throw line with their shots in that game. Their offense is averaging 119 PPG and their defense is allowing their opponents to average 111 PPG against them. The Knicks have an ATS record of 1-0 this season and their O/U record is 1-0.

The current betting odds have the Knicks listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. The Knicks have a 1-0 record overall this season and they looked great in their season opener. They are off a 119-111 win at home over the Cavaliers and they were in control of that entire game. They are in their first year with a new head coach and so far it has been going well as they took an early lead against the Cavs and never really looked back. Meanwhile, the Celtics have a 0-1 record overall this season and they didn't look great in their season opener. They lost at home to the 76ers 117-116 and they are going to be without some key players this season. Tatum is out for the year and they also lost a lot of the talent they had on the team over the last few years so even with Tatum taken out of the equation, this isn't the same team that won the NBA Championship 2 years ago. The Celtics are going to struggle more this season and now they are playing their 1st road game of the year in a tough environment against a divisional rival. The Knicks still have a lot of their talent from last year which made them one of the best teams in the Eastern Conference and they will be looking to take a big step this season with their new coach. The best way to place a bet here is on the Knicks to cover the spread in this game. 

Celtics Knicks Prediction:  Our NBA Pick for Friday, October 24, 2025 (7:30 pm ET start time) is Knicks 124 Celtics 112.

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Boston Celtics: 4-7 ATS as a road underdog. 2-10 ATS when playing against a top-level team (Win Pct. > 70%). 9-2 UNDER as a road underdog. 16-8 UNDER after a loss by 6 points or less.

New York Knicks: 25-18 ATS in a home game where the total is 220 to 229.5. 16-8 ATS when playing against a terrible team (Win Pct. <=25%). 3-0 UNDER at home off an upset win as an underdog.

Boston Celtics:  L. Garza (C) Day To Day - Concussion Protocol. J. Tatum (PF) Out - Achilles.

New York Knicks:  J. Hart (SG) Day To Day - Back.

"I don't know if we were too focused on the offensive end, but we can't let guys just come in here and do what they want." - Jaylen Brown after their loss against the 76ers in their game on Wednesday.

“Our expectations are extremely high, but we're not going to get ahead of ourselves. Whether we won or lost, it's one game, and we feel like as the season goes along, we're going to get better. We won the game and we had some good moments, but we don't feel like we're anywhere near what we're capable of. That's what makes it exciting. Everybody has expectations. I don't know if their expectations are any higher than everybody in that locker room. We're good with that. We embrace that.” - Mike Brown after his team’s win against the Cavaliers in their game on Wednesday.

PG Derrick White

SG Payton Pritchard

SF Jaylen Brown

PF Sam Hauser

C Neemias Queta

PG Jalen Brunson

SG Mikal Bridges

SF OG Anunoby

PF Karl-Anthony Towns

C Ariel Hukporti

PPG: Derrick White (25)

APG: Derrick White (4)

Reb/G: Neemias Queta (8)

PPG: OG Anunoby (24)

APG: Mikal Bridges (6)

Reb/G: OG Anunoby (14)

Coaches:

Boston Celtics: Joe Mazzulla (4th season)

New York Knicks: Mike Brown (1st season)