by Big Al Staff
Sunday, Sep 21, 2025The Sunday sports card features NFL, MLB, and EPL action.
Week 3 in the NFL continues with 14 games. Nine NFL games kick off at 1:00 p.m. ET. The Philadelphia Eagles host the Los Angeles Rams as a 3.5-point favorite with the total set at 44.5 (all odds from DraftKings). The Washington Commanders play at home against the Las Vegas Raiders as a 2.5-point favorite with an over/under of 43.5. The Jacksonville Jaguars are home against the Houston Texans as a 1.5-point favorite with a total of 43.5. The Pittsburgh Steelers travel to New England to play the Patriots as a 1.5-point road favorite with an over/under of 44.5. The Indianapolis Colts play in Tennessee against the Titans as a 5.5-point road favorite with a total of 43.5. The Green Bay Packers are in Cleveland to take on the Browns as an 8.5-point road favorite with an over/under of 41.5. The Atlanta Falcons visit Carolina to face the Panthers as a 4.5-point road favorite with a total of 44.5. The Minnesota Vikings host the Cincinnati Bengals as a 3-point favorite with an over/under of 41.5. The Tampa Bay Buccaneers play at home against the New York Jets as a 6.5-point favorite with a total of 43.5.
Two NFL games start at 4:05 p.m. ET. The Los Angeles Chargers are home against the Denver Broncos as a 2.5-point favorite with an over/under of 45.5. The Seattle Seahawks host the New Orleans Saints as a 7-point favorite with a total of 41.5. Two more NFL games begin at 4:25 p.m. ET. The San Francisco 49ers play at home against the Arizona Cardinals as a 2.5-point favorite with an over/under of 44.5. The Dallas Cowboys play in Chicago against the Bears as a 1.5-point road favorite with a total of 49.5.
The Kansas City Chiefs are on the road in New York to challenge the Giants on NBC at 8:20 PM ET for Sunday Night Football. The Chiefs are a 6-point road favorite with an over/under of 44.5.
Major League Baseball has 15 games on its schedule. Two MLB games throw out the first pitch at 1:35 p.m. ET. The Pittsburgh Pirates are home against the Athletics as a -112 money-line favorite with a total of 8.5. The New York Yankees travel to Baltimore to battle the Orioles as a -137 money-line road favorite with an over/under of 8.5. Three more MLB games start at 1:40 p.m. ET. The New York Mets host the Washington Nationals as a -274 money-line favorite with a total of 8.5. The Cincinnati Reds play at home against the Chicago Cubs as a -115 money-line favorite with an over/under of 9. The Detroit Tigers are home against the Atlanta Braves as a -123 money-line favorite with a total of 8.5.
Three MLB games begin at 2:10 p.m. ET. The San Diego Padres play in Chicago against the White Sox as a -183 money-line road favorite with an over/under of 8. The Cleveland Guardians are in Minnesota to take on the Twins as a -126 money-line road favorite with a total of 8.5. The Toronto Blue Jays visit the Kansas City Royals as a -119 money-line road favorite with an over/under of 9. The Milwaukee Brewers play in St. Louis at 2:35 p.m. ET. The Texas Rangers host the Miami Marlins at 2:35 p.m. ET as a -137 money-line favorite with a total of 7.
The Los Angeles Angels play in Colorado against the Rockies at 3:10 p.m. ET as a -115 money-line road favorite with an over/under of 12. Two more MLB games start at 4:10 p.m. ET. The Philadelphia Phillies are in Arizona to face the Diamondbacks as a -132 money-line road favorite with a total of 9. The Los Angeles Dodgers play at home against the San Francisco Giants as a -220 money-line favorite with an over/under of 9.
Sunday Night Baseball on ESPN features the Seattle Mariners traveling to Houston to play the Astros at 7:10 p.m. ET. The Mariners are a -143 money-line road favorite with a total of 8. The Boston Red Sox play in Tampa Bay against the Rays at 7:35 p.m. ET as a -136 money-line road favorite with an over/under of 8.
Matchweek 5 in the English Premier League concludes with three matches. Two matches begin at 9:00 a.m. ET. Bournemouth is home against Newcastle United on the USA Network as a -0.5 goal-line favorite with a total of 2.5. Aston Villa are on the road against Sunderland as a -0.5 goal-line road favorite with an over/under of 2.5. Arsenal hosts Manchester City at 11:30 a.m. ET as a -0.5 goal-line favorite with a total of 2.5.
