Big Al's Daily Angle: NFL and MLB Previews and Odds - 09/15/2025

by Big Al Staff

Monday, Sep 15, 2025
The Monday sports card features NFL and MLB action. 

Week 2 in the NFL concludes with two games. The Houston Texans host the Tampa Bay Buccaneers on ABC and ESPN at 7:00 p.m. ET. The Texans lost their opening week game on the road in Los Angeles against the Rams by a 14-9 score as a 3-point underdog last Sunday. The Buccaneers come off a 23-20 victory on the road against the Atlanta Falcons as a 1-point favorite on Sunday. Houston is a 2.5-point favorite with the total set at 42.5 (all odds from DraftKings). 

The Los Angeles Chargers travel to Las Vegas to take on the Raiders at 10:00 p.m. ET. The Chargers upset Kansas City in their first game of the season in Brazil by a 27-21 score as a 3-point underdog two Fridays ago. The Raiders pulled off a 20-13 upset win at New England against the Patriots as a 2.5-point underdog on Sunday. Los Angeles is a 3.5-point road favorite with an over/under of 46.5. 

Major League Baseball has nine games on its schedule. The Chicago Cubs play in Pittsburgh against the Pirates at 6:40 p.m. ET. The Cubs send out Jameson Taillon to pitch against the Pirates’ Braxton Ashcraft. Chicago is a -136 money-line road favorite with a total of 8. The Atlanta Braves are in Washington to play the Nationals at 6:45 p.m. ET. Spencer Strider takes the ball for the Braves to battle Mitchell Parker for the Nationals. Atlanta is a -157 money-line road favorite with an over/under of 9. 

The Toronto Blue Jays visit Tampa Bay to play the Rays at 7:35 p.m. ET. The Blue Jays are calling up Trey Yesavage to take the mound to duel against a Rays’ starting pitcher yet to be named. Two more MLB games throw out the first pitch at 7:40 p.m. ET. Baltimore plays in Chicago with Kyle Bradish taking the ball for the Orioles to challenge Tyler Gilbert for the White Sox. The Orioles are a -151 money-line road favorite with a total of 8. The St. Louis Cardinals play at home against the Cincinnati Reds at 7:45 p.m. ET. The Cardinals send out Matthew Liberatore to take on the Reds’ Zack Littell. St. Louis is a -126 money-line favorite with an over/under of 8.5. 

The Houston Astros are home against the Texas Rangers at 8:10 p.m. ET. Jason Alexander gets the ball for the Astros to face Jack Leiter for the Ranges. Houston is a -126 money-line favorite with a total of 8.5. The Arizona Diamondbacks host the San Francisco Giants at 9:40 p.m. ET. The Diamondbacks turn to Zac Gallen to face the Giants’ Kai-Wei Teng. San Francisco is a -150 money-line favorite with an over/under of 9.5. The Los Angeles Dodgers play at home against the Philadelphia Phillies at 10:10 p.m. ET. Emmett Sheehan takes the hill for the Dodgers to pitch against Ranger Suarez for the Phillies. Los Angeles is a -137 money-line favorite with a total of 8.5. 






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