Big Al's Daily Angle: NFL and MLB Previews and Odds - 09/07/2025

by Big Al Staff

Sunday, Sep 07, 2025
The Sunday sports card features NFL and MLB action. 

Week 1 in the NFL continues with 13 games. Eight NFL games kick off at 1:00 p.m. ET. The Indianapolis Colts host the Miami Dolphins as a 1.5-point favorite with the total set at 47.5 (all odds DraftKings). The Pittsburgh Steelers travel to New York to play the Jets as a 3-point road favorite with an over/under of 37.5. The Washington Commanders play at home against the New York Giants as a 6-point favorite with a total of 45.5. The Jacksonville Jaguars are home against the Carolina Panthers as a 3.5-point favorite with an over/under of 46.5. The Arizona Cardinals play in New Orleans against the Saints as a 6.5-point road favorite with a total of 43.5. The Cincinnati Bengals are in Cleveland to take on the Browns as a 5.5-point road favorite with an over/under of 48.5. The New England Patriots host the Las Vegas Raiders as a 2.5-point favorite with a total of 44.5. The Tampa Bay Buccaneers visit Atlanta to face the Falcons as a 1.5-point road favorite with an over/under of 47.5. 

Two NFL games start at 4:05 p.m. ET. The Denver Broncos play at home against the Tennessee Titans as an 8.5-point favorite with a total of 42.5. The San Francisco 49ers play in Seattle to battle the Seahawks as a 1.5-point road favorite with an over/under of 43.5. 

Two more NFL games begin at 4:25 p.m. ET. The Green Bay Packers are home against the Detroit Lions as a 1.5-point favorite with a total of 47.5. The Los Angeles Rams host the Houston Texans as a 3.5-point favorite with an over/under of 43.5.

The Baltimore Ravens are in Buffalo to take on the Bills on NBC at 8:20 PM ET for Sunday Night Football. The Ravens are a 1.5-point road favorite with a total of 50.5.  

Major League Baseball has 15 games on its schedule. The Atlanta Braves play at home against the Seattle Mariners at 12:05 p.m. ET as a -126 money-line favorite with an over/under of 9. The Tampa Bay Rays are home against the Cleveland Guardians at 12:10 p.m. ET as a -149 money-line favorite with a total of 8. 

Three MLB games throw out the first pitch at 1:35 p.m. ET. The Milwaukee Brewers travel to Pittsburgh to battle the Pirates as a -150 money-line road favorite with an over/under of 8. The New York Yankees host the Toronto Blue Jays as a -157 money-line favorite with a total of 8.5. The Los Angeles Dodgers play in Baltimore to take on the Orioles as a -165 money-line road favorite with an over/under of 9. 

Three MLB games start at 1:40 p.m. ET. The Cincinnati Reds play at home against the New York Mets as a -127 money-line favorite with a total of 8.5. The Detroit Tigers are home against the Chicago White Sox as a -182 money-line favorite with an over/under of 9. 

The Kansas City Royals host the Minnesota Twins at 2:10 p.m. ET as a -137 money-line favorite with a total of 8.5. The St. Louis Cardinals host the San Francisco Giants at 2:15 p.m. ET as a -150 money-line favorite with an over/under of 8. The Chicago Cubs play at home against the Washington Nationals at 2:20 p.m. ET as a -200 money-line favorite with a total of 8.5. The Houston Astros are in Texas to face the Rangers at 2:35 p.m. ET as a -126 money-line road favorite with an over/under of 8.5. 

The San Diego Padres visit Colorado to challenge the Rockies at 3:10 p.m. ET as a -232 money-line road favorite with a total of 11.5. The Athletics play in Los Angeles against the Angels at 4:07 p.m. ET as a -120 money-line road favorite with an over/under of 9.5. The Boston Red Sox are in Arizona to play the Diamondbacks at 4:10 p.m. ET as a -112 money-line road favorite with a total of 9.

All photographic images used for editorial content have been licensed from the Associated Press.

© 2025 Al McMordie's BigAl.com. All Rights Reserved.