Big Al's Daily Angle: NFL and MLB Previews and Odds - 09/04/2025

by Big Al Staff

Thursday, Sep 04, 2025
The Thursday sports card features NFL and MLB action.

The National Football League kicks off its 2025-26 regular season with the Philadelphia Eagles hosting the Dallas Cowboys on NBC-TV at 8:20 p.m. ET. The Eagles come off an 18-3 season that ended with their 40-22 victory against Kansas City in the Super Bowl. The Cowboys come off a 7-10 record last year. Philadelphia swept both games against Dallas last year after 34-6 and 41-7 victories in the regular season. The Eagles are an 8.5-point favorite with the total set at 47.5 (all odds from DraftKings). 

Major League Baseball has six games scheduled. The Milwaukee Brewers play at home against the Philadelphia Phillies at 4:10 p.m. ET. The Brewers ended a two-game losing streak with a 6-3 victory against the Phillies on Wednesday. Philadelphia has lost two of its last three games. Milwaukee sends out Freddy Peralta to pitch against the Phillies’ Ranger Suarez. The Phillies are a -128 money-line favorite with an over/under of 8.  

The Los Angeles Dodgers travel to Pittsburgh to take on the Pirates at 6:40 p.m. ET. The Dodgers lost for the fourth time in their last five games after their 3-0 loss on the road against the Pirates on Wednesday. Pittsburgh has won four of its last five games. Blake Snell gets the ball for Los Angeles to challenge Paul Skenes for the Pirates. The Dodgers are a -121 money-line road favorite with a total of 7. 

The Tampa Bay Rays are home against the Cleveland Guardians at 7:35 p.m. ET. The Rays have won six games in a row after a 9-4 victory against Seattle yesterday. The Guardians ended a three-game losing streak with an 8-1 victory at Boston on Wednesday. Tampa Bay turns to Ryan Pepiot to face the Guardians’ Logan Allen. The Rays are a -150 money-line favorite with an over/under of 8.5. 

Three MLB games throw out the first pitch at 7:40 p.m. ET. The New York Yankees play in Houston against the Astros. The Yankees lost for the second time in their last three games after an 8-7 loss on the road against the Astros. Houston has won two of their last three games. Carlos Rodon takes the hill for the Yankees to battle Cristian Javier for the Astros. New York is a -137 money-line road favorite with a total of 8.5. 

The Kansas City Royals host the Los Angeles Angels. The Royals are on a three-game losing streak after a 4-3 loss against the Angels. Los Angeles has won four of their last five games. Kansas City taps Noah Cameron to take on the Angels’ Kyle Hendricks. The Royals are a -158 money-line favorite with an over/under of 9. 

The Minnesota Twins play at home against the Chicago White Sox. The  Twins are on a three-game losing streak after their 4-3 loss at home against the White Sox. Chicago has won four games in a row. Taj Bradley gets the ball for Minnesota to face the White Sox’s Shane Smith. The Twins are a -158 money-line favorite with a total of 8.5. 

All photographic images used for editorial content have been licensed from the Associated Press.

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