Big Al's Daily Angle: NCAAF, MLB, CFL and EPL Previews and Odds - 09/20/2025

by Big Al Staff

Saturday, Sep 20, 2025
The Saturday sports card features NCAAF, MLB, CFL, and EPL action.

Week 4 in NCAAF college football continues with 47 games between FBS opponents. Seven NCAAF games on major national television kick off at noon ET. TCU hosts SMU on ESPN2 as a 6.5-point favorite with the total set at 63.5 (all odds from DraftKings). North Texas travels to play the Army on the CBS Sports Network as a 2.5-point road favorite with an over/under of 50.5. Arkansas plays at Memphis on ABC as a 7-point road favorite with a total of 60.5. Wisconsin plays at home against Maryland on NBC as a 10-point favorite with an over/under of 44.5. UNLS is at Miami (OH) as a 2.5-point road favorite with a total of 49.5. Utah is at home against Texas Tech on Fox as a 3.5-point favorite with an over/under of 57.5. Clemson hosts Syracuse on ESPN as a 17.5-point favorite with a total of 54.5. 

Seven NCAAF games on major national television start at 3:30 p.m. ET. Central Florida plays at home against North Carolina on Fox as a 7-point favorite with an over/under of 46.5. UConn is home against Ball State on the CBS Sports Network as a 21.5-point favorite with a total of 53.5. Oklahoma hosts Auburn on ABC at 3:30 p.m. ET as a 6.5-point favorite with an over/under of 46.5. Michigan visits Nebraska on CBS as a 1.5-point road favorite with a total of 47.5. Mississippi plays at home against Tulane on ESPN as an 11.5-point favorite with an over/under of 61.5. Notre Dame is home against Purdue on NBC as a 24.5-point favorite with a total of 51.5. James Madison plays at Liberty on ESPNU as an 8.5-point road favorite with an over/under of 46.5. Duke hosts North Carolina State on ESPN2 at 4:00 p.m. ET as a 3-point favorite with a total of 57.5. Kansas plays at home against West Virginia on FS1 at 6:00 p.m. ET as a 12.5-point favorite with an over/under of 54.5. 

Two NCAAF games on major national television start at 7:00 p.m. ET. Missouri is home against South Carolina on ESPN as a 10-point favorite with a total of 48.5. Boise State is at the Air Force on the CBS Sports Network as an 11.5-point road favorite with an over/under of 51.5. Six more NCAAF games on major national television begin at 7:30 p.m. ET. Indiana hosts Illinois on NBC as a 6.5-point favorite with a total of 52.5. Washington travels to Washington State on CBS as a 21-point road favorite with an over/under of 51.5. Vanderbilt plays at home against Georgia State on ESPNU as a 27.5-point favorite with a total of 52.5. Baylor is home against Arizona State on Fox as a 2.5-point favorite with an over/under of 59.5. Miami (FL) hosts Florida on ABC as a 7.5-point favorite with a total of 50.5. BYU plays at East Carolina on ESPN2 as a 6.5-point road favorite with an over/under of 49.5. UTSA is at Colorado State on FS1 at 9:30 p.m. ET as a 4.5-point road favorite with a total of 58.5. Colorado plays at home against Wyoming on ESPN at 10:15 p.m. ET as a 12.5-point favorite with an over/under of 45.5. California visits San Diego State on the CBS Sports Network at 10:30 p.m. ET as a 14-point road favorite with a total of 46.5. USC is home against Michigan State on Fox as an 18.5-point favorite with an over/under of 55.5. 

Major League Baseball has 16 games scheduled. The Detroit Tigers host the Atlanta Braves at 1:10 p.m. ET as a -126 money-line favorite with a total of 9. The Minnesota Twins play at home against the Cleveland Guardians in the first game of their doubleheader. The New York Mets are home against the Washington Nationals at 4:10 p.m. ET as a -261 money-line favorite with an over/under of 8.5. 

Two MLB games throw out the first pitch at 6:40 p.m. ET. The Chicago Cubs play at Cincinnati against the Reds as a -112 money-line road favorite with a total of 8.5. The Athletics are in Pittsburgh against the Pirates as a -112 money-line road favorite with an over/under of 8.5. 

Three MLB games start at 7:05 p.m. ET. The Tampa Bay Rays host the Boston Red Sox as a -112 money-line favorite with a total of 8.5. The Texas Rangers play at home against the Miami Marlins as a -162  money-line favorite with an over/under of 9. The New York Yankees travel to Baltimore against the Orioles as a -205 money-line road favorite with a total of 9. 

Four MLB games begin at 7:10 p.m. ET. The San Diego Padres play in Chicago against the White Sox as a -172 money-line road favorite with an over/under of 8.5. The Houston Astros are home against the Seattle Mariners as a -113 money-line favorite with a total of 8. The Twins host the Guardians in the second game of their doubleheader. The Toronto Blue Jays are in Kansas City against the Royals as a -157 money-line road favorite with an over/under of 8. The Milwaukee Brewers visit St. Louis to face the Cardinals at 7:15 p.m. ET as a -150 money-line road favorite with a total of 9. 

Two MLB games start at 8:10 p.m. ET. The Arizona Diamondbacks play at home against the Philadelphia Phillies as a -119 money-line favorite with an over/under of 9. The Los Angeles Angels play at Colorado as a -132 money-line road favorite with a total of 11.5. The Los Angeles Dodgers are home against the San Francisco Giants at 9:10 p.m. ET as a -239 money-line favorite with an over/under of 8.5.

Week 16 in the Canadian Football League concludes with two games. The Ottawa Redblacks host the Winnipeg Blue Bombers at 3:00 p.m. ET as a 3-point favorite with a total of 52.5. The Hamilton Tiger-Cats play at home against the Edmonton Elks at 7:00 p.m. ET as a 5.5-point favorite with an over/under of 55.5.

Matchweek 5 in the English Premier League begins with seven matches. Liverpool is home against Everton on the USA Network at 7:30 a.m. ET as a -1.5 goal-line favorite with a total of 2.5. Four more EPL matches begin at 10:00 a.m. ET. Brighton and Hove Albion hosts Tottenham as a -0.5 goal-line favorite with an over/under of 2.5. Nottingham Forest is at Burnley as a -0.5 goal-line road favorite with a total of 2.5. Crystal Palace travels to West Ham United on the USA Network as a -0.5 goal-line road favorite with an over/under of 2.5. Leeds United plays at Wolverhampton as a -0.5 goal-line road favorite with a total of 2.5. Manchester United plays at home against Chelsea on the USA Network at 12:30 p.m. ET as a -0.5 goal-line favorite with an over/under of 3.5. Fulham is home against Brentford on the USA Network at 3:00 p.m. ET as a -0.5 goal-line favorite with a total of 2.5. 

All photographic images used for editorial content have been licensed from the Associated Press.

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