Big Al's Daily Angle: NCAAF, MLB and CFL Previews and Odds - 09/19/2025

by Big Al Staff

Friday, Sep 19, 2025
The Friday sports card features NCAAF, MLB, and CFL action. 

Week 4 in NCAAF college football continues with two games between FBS opponents. Oklahoma State hosts Tulsa on ESPN at 7:30 p.m. ET as a 10.5-point favorite with the total set at 54.5 all odds from DraftKings). Iowa travels on the road to play Rutgers on Fox at 8:00 p.m. ET as a 2.5-point road favorite with an over/under of 45.5. 

Major League Baseball has 15 games on its schedule. Three MLB games throw out the first pitch at 6:40 p.m. ET. The Athletics play away from home at Pittsburgh against the Pirates, with both teams priced as a -110 money-line favorite with a total of 8.5. The Detroit Tigers play at home against the Atlanta Braves as a -123  money-line favorite with an over/under of 9. The Chicago Cubs are in Cincinnati to take on the Reds as a -126 money-line road favorite with a total of 8.5. 

The  New York Yankees visit Baltimore to face the Orioles at 7:05 p.m. ET as a -121 money-line road favorite with an over/under of 9. The New York Mets are home against the Washington Nationals at 7:10 p.m. ET as a -208 money-line favorite with a total of 8.5. The Boston Red Sox play in Tampa Bay against the Rays at 7:35 p.m. ET as a -132 money-line road favorite with an over/under of 7. 

Two MLB games start at 7:40 p.m. ET. The San Diego Padres are in Chicago to challenge the White Sox as a -169 money-line road favorite with a total of 8. The Toronto Blue Jays travel to Kansas City to play the Royals as a -144 money-line road favorite with an over/under of 9. The Texas Rangers host the Miami Marlins at 8:05 p.m. ET as a -165 money-line favorite with a total of 8.5. 

Four MLB games begin at 8:10 p.m. ET. The Houston Astros play at home against the Seattle Mariners as a -112 money-line favorite with an over/under of 7.5. The Los Angeles Angels play in Colorado against the Rockies as a -123 money-line road favorite with a total of 12. The Minnesota Twins are home against the Cleveland Guardians as a -120 money-line favorite with an over/under of 8. The Milwaukee Brewers are in St. Louis to battle the Cardinals as a -121 money-line road favorite with a total of 7.5. 

The Arizona Diamondbacks host the Philadelphia Phillies at 9:40 p.m. ET as a -126 money-line favorite with an over/under of 9.5. The Los Angeles Dodgers play at home against the San Francisco Giants at 10:10 p.m. ET as a -172 money-line favorite with a total of 8.5. 

Week 16 in the Canadian Football League kicks off with two games. The Montreal Alouettes visit the Toronto Argonauts at 7:00 p.m. ET as a 6.5-point road favorite with an over/under of 50.5. The Calgary Stampeders are home against the British Columbia Lions at 9:30 p.m. ET as a 5.5-point favorite with a total of 55.5.

All photographic images used for editorial content have been licensed from the Associated Press.

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