Big Al's Daily Angle: NCAAF, MLB and CFL Previews and Odds - 09/12/2025

by Big Al Staff

Friday, Sep 12, 2025
The Friday sports card features NCAAF, MLB, and CFL action.

Week 3 in NCAAF college football continues with three games between FBS opponents. Houston hosts Colorado on ESPN at 7:30 p.m. ET as a 4-point favorite with the total set at 44.5 (all odds from DraftKings). Kansas State travels to Arizona on Fox at 9:00 p.m. ET as a 1.5-point road favorite with an over/under of 54.5. UCLA plays at home against New Mexico at 10:00 p.m. ET as a 14.5-point favorite with a total of 52.5.

Major League Baseball has 15 games on its schedule. The Chicago Cubs are home against the Tampa Rays at 2:20 p.m. ET as a -172 money-line favorite with an over/under of 7.5. 

Two MLB games throw out the first pitch at 6:45 p.m. ET. The Washington Nationals host the Pittsburgh Pirates as a -112 money-line favorite with a total of 8. The Philadelphia Phillies play at home against the Kansas City Royals as a -137 money-line favorite with an over/under of 9. 

The Toronto Blue Jays are home against the Baltimore Orioles at 7:07 p.m. ET as a -137 money-line favorite with a total of 8. 

Four MLB games start at 7:10 p.m. ET. The New York Yankees play in Boston against the Red Sox on Apple TV+ as a -123 money-line road favorite with an over/under of 9. The Texas Rangers are in New York to take on the Mets, with both teams priced as a -110 money-line favorite with a total of 7.5. The Cleveland Guardians host the Chicago White Sox as a -175 money-line favorite with an over/under of 7.5. The Detroit Tigers visit Miami to face the Marlins as a -207 money-line road favorite with a total of 7. The Houston Astros play in Detroit against the Tigers at 7:15 p.m. ET.  

Two MLB games begin at 8:10 p.m. ET. The Milwaukee Brewers play at home against the St. Louis Cardinals as a -187 money-line favorite with an over/under of 8.5. The Minnesota Twins are home against the Arizona Diamondbacks as a -132 money-line favorite with a total of 8.5. 

The San Diego Padres host the Colorado Rockies at 9:40 p.m. ET as a -316 money-line favorite with an over/under of 8. The Cincinnati Reds are on the road against the Athletics at 10:05 p.m. ET. 

The Seattle Mariners play at home against the Los Angeles Angels on Apple TV+ at 10:10 p.m. ET as a -176 money-line favorite with a total of 8. 

The Los Angeles Dodgers travel to San Francisco to battle the Giants at 10:15 p.m. ET as a -158 money-line road favorite with an over/under of 7.5.  

Week 15 in the Canadian Football League kicks off with two games on the CBS Sports Network. The Hamilton Tiger-Cats host the Winnipeg Jets at 7:00 p.m. ET as a 7-point favorite with an over/under of 51.5. The British Columbia Lions play at home against the Ottawa Redblacks at 10:00 p.m. ET as an 8.5-point favorite with a total of 56.5. 

All photographic images used for editorial content have been licensed from the Associated Press.

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