Big Al's Daily Angle: MLB and UEFA Champions League Previews and Odds - 09/16/2025

by Big Al Staff

Tuesday, Sep 16, 2025
The Tuesday sports card features MLB and UEFA Champions League action. 

Major League Baseball has 16 games on its schedule. The Atlanta Braves travel to Washington to play the Nationals in the opening game of their doubleheader at 1:05 p.m. ET to make up for a postponed contest on May 21st. 

Two MLB games throw out the first pitch at 6:40 p.m. ET. The Pittsburgh Pirates host the Chicago Cubs as a -131 money-line favorite with an over/under of 7 (all odds from DraftKings). The Detroit Tigers host the Cleveland Guardians as a -157 money-line favorite with a total of 8. 

Two MLB games start at 6:45 p.m. ET. The Boston Red Sox play at home against the Athletics as a -164 money-line favorite with an over/under of 9. The Braves battle the Nationals in the second game of their doubleheader as a -187 money-line road favorite with a total of 7. 

The San Diego Padres are in New York to take on the Mets on TBS at 7:10 p.m. ET, with both teams priced at -110 with an over/under of 8.5. The Tampa Bay Rays are home against the Toronto Blue Jays at 7:35 p.m. ET as a -112 money-line favorite with a total of 8.5. 

Four MLB games begin at 7:40 p.m. ET. The Chicago White Sox host the Baltimore Orioles as a -132 money-line favorite with an over/under of 8. The Milwaukee Brewers play at home against the Los Angeles Angels as a -268 money-line favorite with a total of 8.5. The New York Mets visit Minnesota to face the Twins as a -176 money-line favorite with an over/under of 9. The Seattle Mariners play in Kansas City against the Royals as a -143 money-line road favorite with a total of 8.5. The Cincinnati Reds are in St. Louis to challenge the Cardinals at 7:45 p.m. ET as a -115 money-line road favorite with an over/under of 8. 

The Texas Rangers travel to Houston to play the Astros at 8:10 p.m. ET as a -137 money-line road favorite with a total of 8. The Miami Marlins play in Colorado to face the Rockies at 8:40 p.m. ET as a -157 money-line road favorite with an over/under of 10. 

The Arizona Diamondbacks are home against the San Francisco Giants at 9:40 p.m. ET. The Los Angeles Dodgers host the Philadelphia Phillies on TBS at 10:10 p.m. ET as a -115 money-line favorite with a total of 7.5.

Matchday 1 in the UEFA Champions League begins with six league phase matches. Two matches start at 12:45 PM ET. PSV Eindhoven plays at home against Saint Gilloise on the CBS Sports Network as a -0.5 goal-line favorite with an over/under of 2.5. Arsenal is on the road against Athletic Bilbao as a -0.5 goal-line road favorite with a total of 2.5. 

Six matches conclude the UCL card at 3 PM ET. Real Madrid is home against Marseille as a -1.5 goal-line favorite with an over/under of 3.5. Benfica is home against FK Qarabag on the CBS Sports Network as a -1.5 goal-line favorite with a total of 3.5. Juventus hosts Borussia Dortmund as a -0.5 goal-line favorite with an over/under 2.5. Tottenham plays at home against Villarreal as a -0.5 goal-line favorite with a total of 2.5. All eight Champions League matches are available on Paramount+.

All photographic images used for editorial content have been licensed from the Associated Press.

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