Baltimore Orioles vs Seattle Mariners Prediction, Preview and Odds - 06/17/2026

Game Time: 9:40 pm ET, Wednesday, June 17, 2026

Venue:  T-Mobile Park, Seattle, WA

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Orioles +123, Mariners -149; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  Orioles +125, Mariners -150; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  Orioles +125, Mariners -155; Over/Under:  7.5 runs

Baltimore Orioles:  34-39 (4th place, AL East)

Seattle Mariners:  37-36 (1st place, AL West)

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Baltimore Orioles:  4-6 last 10

Seattle Mariners:  4-6 last 10

The Orioles are entering this series off a loss and lost their 3-game series against the San Diego Padres 2-1 in their last series. They enter this game with a 34-39 record overall and have a road record of 12-20. This is the 2nd game of a 3-game series with the Mariners on Wednesday with the series opener still to be played on Tuesday. Their offense ranks 11th in the MLB with a .728 OPS. Brandon Young is their starting pitcher on Tuesday while Kyle Bradish is making his start in this game on Wednesday. He is 3-7 with a 4.30 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 5 ER, 3 HR, and 3 BB with 5 SO on 7 hits through 4 IP against the Seattle Mariners.

The Mariners are entering this series off a loss and lost their 3-game series against the Washington Nationals 2-1 in their last series. They enter this game with a 37-36 record overall and have a home record of 19-16. This is the 2nd game of a 3-game series with the Orioles on Wednesday with the 1st game of this series still to be played on Tuesday. Their offense ranks 17th in the MLB with a .713 OPS. Logan Gilbert is their starting pitcher on Tuesday while George Kirby is making his start in this game on Wednesday. He is 5-6 with a 4.07 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 3 earned runs, 1 homer, and 3 walks with 10 strikeouts on 7 hits through 6 innings pitched against the Baltimore Orioles.

The current betting odds have the Mariners listed as a favorite in this game according to Draftkings Sportsbook. The Mariners have looked good in their games this season with their 37-36 record overall which has them right at the top of the AL West. They have looked better in their own ballpark too with their 19-16 home record this season. Meanwhile, the Orioles haven't looked good in their games this season with their 34-39 record overall which has them right near the bottom of the AL East. They have been a terrible road team too with their 12-20 road record this year. Neither team has looked great lately as both are 4-6 in their last 10 games respectively and they just split a 4-game series last week. The Mariners have also been cooling off lately, but they are going to have the better pitching matchup in this one and the Orioles have been giving up a ton of runs lately. Bradish is on the mound for the Orioles in this one and he hasn't looked great this season. He is 3-7 with a 4.30 ERA and he has been giving up quite a few runs this year. His team has been having success with him lately, winning 3 of their last 4 games with him starting, but he did give up 5 earned runs in his last start and that has been a common theme for him. Kirby is on the mound for the Mariners in this one and he hasn't looked great this season either. He is 5-6 with a 4.07 ERA and his team hasn't been having a ton of success with him lately. They have lost 2 games in a row now with him starting, but he only gave up 3 earned runs in his last start and he hasn't been giving up as many runs at home either. Kirby will be the better starter here and the Mariners bullpen has been more trustworthy over the course of the season. The best way to place a bet here is on the Mariners to win this game. 

Orioles Mariners Prediction:  Our MLB Pick for Wednesday, June 17, 2026 (9:40 pm ET start time) is Mariners 5 Orioles 4.

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Baltimore Orioles: 200-199 (-23.5 units) on the moneyline in all games. 148-139 (-12.5 units) on the moneyline against right-handed starters. 95-106 (-10 units) on the moneyline when playing against a team with a winning record. 22-12 OVER as an underdog of +100 or higher.

Seattle Mariners: 122-81 (+14.9 units) on the moneyline in home games. 103-65 (+9.4 units) on the moneyline as a home favorite of -110 or higher. 97-54 (+25.9 units) on the moneyline at home when the total is 7 to 7.5. 17-10 OVER as a home favorite of -125 to -175.

Baltimore Orioles:  C. Bassitt (SP) Fifteen Day IL - Back. D. Beavers (RF) Ten Day IL - Oblique. C. Povich (SP) Fifteen Day IL - Elbow. R. Helsley (RP) Fifteen Day IL - Elbow. D. Kremer (SP) Sixty Day IL - Quad. R. Mountcastle (1B) Sixty Day IL - Foot. Y. Hiraldo (RP) Sixty Day IL - Shoulder. Z. Eflin (SP) Sixty Day IL - Elbow. J. Westburg (3B) Sixty Day IL - UCL. F. Bautista (RP) Sixty Day IL - Shoulder. C. Selby (SP) Sixty Day IL - Shoulder.

Seattle Mariners:  A. Munoz (RP) Day To Day - Back. J. Naylor (1B) Day To Day - Leg. R. Arozarena (LF) Day To Day - Leg. M. Brash (RP) Fifteen Day IL - Lat. C. Criswell (RP) Fifteen Day IL - Shoulder. J. Crawford (SS) Ten Day IL - Hand. B. Donovan (3B) Ten Day IL - Groin. C. Raleigh (C) Ten Day IL - Side. W. Wilson (3B) Ten Day IL - Thumb. C. Vargas (RP) Sixty Day IL - Lat. L. Evans (SP) Sixty Day IL - Arm.

“It was tough. Just did my job, executed pitches, got the ball on the ground. This game is a game of inches and you could either let it affect the rest of the day, or as soon as the ball hits the bag, you’ve just got to laugh at stuff like that.” - Trevor Rogers after their loss against the Padres in their game on Sunday. 

“A chance for him to make sure he was OK, and get him off of his feet for the rest of that one.” - Dan Wilson on the injury to Josh Naylor after his team’s loss against the Nationals in their game on Sunday. 

Taylor Ward (R) LF

Gunnar Henderson (L) SS

Adley Rutschman (S) DH

Pete Alonso (R) 1B

Samuel Basallo (L) C

Leody Taveras (S) RF

Colton Cowser (L) CF

Jeremiah Jackson (R) 2B

Blaze Alexander (R) 3B

Cole Young (L) 2B

Julio Rodríguez (R) DH

Josh Naylor (L) 1B

Luke Raley (L) LF

Dominic Canzone (L) RF

Victor Robles (R) CF

Miles Mastrobuoni (L) 3B

Jhonny Pereda (R) C

Colt Emerson (L) SS

Batting Average:  Blaze Alexander (.303)

Hits:  Pete Alonso (70)

Home Runs:  Pete Alonso (16)

RBI:  Pete Alonso (48)

Stolen Bases:  Leody Taveras (8)

Wins:  Brandon Young (5)

Saves:  Ryan Helsley (7)

ERA:  Jose Espada (0.00)

Batting Average:  Randy Arozarena (.291)

Hits:  Randy Arozarena (76)

Home Runs:  Luke Raley (14)

RBI:  Luke Raley (35)

Stolen Bases:  Randy Arozarena (19)

Wins:  George Kirby (5)

Saves:  Andrés Muñoz (10)

ERA:  Nick Davila (0.00)

Managers:

Baltimore Orioles: Craig Albernaz (1st season)

Seattle Mariners: Dan Wilson (3rd season)