Game Time: 7:00 pm ET, Saturday, September 13, 2025
Venue: Vaught Hemingway Stadium, Oxford, MS
Where to Watch: ESPN
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Arkansas +7, Ole Miss -7; Over/Under: 61.5 points
Bet365: Point Spread: Arkansas +7, Ole Miss -7; Over/Under: 61 points
BetMGM: Point Spread: Arkansas +7, Ole Miss -7; Over/Under: 60.5 points
Season Record
Arkansas Razorbacks: 2-0 (0-0) (3rd place, SEC)
Mississippi Rebels: 2-0 (1-0) (1st place, SEC)
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Arkansas Razorbacks: won their last game at home against the Arkansas State Red Wolves 56-14.
Mississippi Rebels: won their last game on the road against the Kentucky Wildcats 30-23.
Arkansas Razorbacks vs Mississippi Rebels Preview and Analysis
Arkansas is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Arkansas State 56-14. Taylen Green was the starting QB and he completed 17/26 passes for 239 passing yards, 4 touchdowns, and 2 interceptions. Taylen Green led the team in rushing yards with 151 and 1 TD. Rohan Jones led the receivers with 74 receiving yards on 2 receptions and 1 TD. Xavian Sorey Jr. led the defense in that game with 6 solo tackles and 9 assisted tackles while Quincy Rhodes Jr. led the defense in sacks with 2. Xavian Sorey Jr. and Julian Neal each came away with 1 interception for them in that one.
Ole Miss is entering this game with a 2-0 record overall and they have a 1-0 record in their conference games too. They are 1-0 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Kentucky 30-23. Austin Simmons was the starting QB and he completed 13/24 passes for 235 passing yards, 0 touchdowns, and 2 interceptions. Kewan Lacy led the team in rushing yards with 138 and 1 TD. Harrison Wallace III led the receivers with 117 receiving yards on 4 receptions. Kapena Gushiken led the defense in that game with 5 solo tackles and 0 assisted tackles while Zxavian Harris, William Echoles, and Princewill Umanmielen each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Arkansas vs Mississippi Prediction
The current betting odds have Ole Miss listed as a 7 point favorite in this game according to Draftkings Sportsbook. Ole Miss has a 2-0 record overall this season and they have looked good in their 2 games. They demolished Georgia State in their season opener and now they have a conference win under their belt with Kentucky. They didn't look great in that road win against Kentucky, only winning 30-23 and struggling to pull away in that one, but they did lose that game at home last year and have struggled with Kentucky in the past. Arkansas isn't a team that they have struggled with though, beating them on the road by over 30 points last season, and this game is going to be no different at home. Meanwhile, Arkansas has a 2-0 record overall this season and they have looked great in their games so far. Their offense has been rolling with over 50 points scored in both games, but they also haven't played any tough opponents. The defense hasn't looked that great either and that is going to be an issue against this Ole Miss team that can put up points on offense at home. Ole Miss also has a test under their belt already with that road win in Kentucky last week while this is going to be the first true test for Arkansas this year, and it comes on the road against a ranked conference opponent. The best way to place a bet here is on Ole Miss to cover the spread in this game.
Arkansas Mississippi Prediction: Our NCAAF Pick for Saturday, September 13, 2025 (7:00 pm ET start time) is Ole Miss 35 Arkansas 23.
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NCAAF Betting Trends
Arkansas Razorbacks: 2-5 ATS after a win by 17 or more points. 4-7 ATS after 1 or more consecutive straight up wins. 4-1 OVER as an underdog of 3.5 to 10 points. 5-2 OVER after scoring 37 points or more last game.
Mississippi Rebels: 16-10 ATS in all lined games. 9-5 ATS in home lined games. 5-1 ATS off a road win. 26-19 OVER at home in the first month of the season.
Key Injuries
Arkansas Razorbacks: D. Oke (DL) Questionable - Undisclosed. A. Jordan (WR) Out - Ankle. I. Cisse (WR) Out - Wrist.
Mississippi Rebels: L. Hasz (TE) Probable - Ankle. A. Simmons (QB) Probable - Undisclosed. S. Reed (WR) Questionable - Undisclosed. T. Ray (WR) Questionable - Undisclosed. T. Davis (OG) Questionable - Undisclosed. D. Core (CB) Questionable - Undisclosed. J. Braxton (CB) Questionable - Undisclosed. R. Fletcher (CB) Questionable - Undisclosed.
Notable Quotes
“We’ll think about the two picks, we got that corrected with his eyes and where to go with the ball after the second quarter. But he was outstanding with his legs. When he takes off, you just know you’re going to get a first down, and then what happens after that is just extra gravy. He threw the ball to eight guys. Our protection was great. I know he didn’t have to scramble much. I bet our average per carry was high.” - Sam Pittman on Taylen Green after his team’s win against Arkansas State in their last game.
“To come on the road in the SEC and win is hard. That game toward the end was like last year, but all three phases went our way this year.” - Lane Kiffin after his team’s win against Kentucky in their last game.
Starting Lineups
Arkansas Razorbacks
WR Blake, O'Mega
WR Brown, Jalen
WR Brown, CJ
TE Jones, Rohan
QB Green, Taylen
RB Washington Jr., Mike
FB Lassiter, Maddox
Mississippi Rebels
WR Wallace III, Harrison
WR Stribling, De'Zhaun
WR Lee, Cayden
TE Wright, Dae'Quan
QB Simmons, Austin
RB Lacy, Kewan
Statistical Leaders
Arkansas Razorbacks
Passing: T. Green (561)
Rushing: M. Washington Jr. (195)
Receiving: O. Blake (185)
Touchdowns: O. Blake (2)
Mississippi Rebels
Passing: A. Simmons (576)
Rushing: K. Lacy (246)
Receiving: H. Wallace III (247)
Touchdowns: K. Lacy (4)
Coaches:
Arkansas Razorbacks: Sam Pittman (6th season)
Mississippi Rebels: Lane Kiffin (6th season)