Arizona Diamondbacks vs San Diego Padres Prediction, Preview and Odds - 07/08/2025

Game Time: 9:40 pm ET, Tuesday, July 8, 2025

Venue:  Petco Park, San Diego, CA 

Where to Watch:  DBACKS.tv, PADRES.tv 

DraftKings:  Moneyline odds:  Diamondbacks -101, Padres -121; Over/Under:  8 runs

Bet365:  Moneyline odds:  Diamondbacks +100, Padres -120; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Diamondbacks +100, Padres -120; Over/Under:  8 runs

Arizona Diamondbacks:  44-46 (4th place, NL West)

San Diego Padres:  48-41 (2nd place, NL West)

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Arizona Diamondbacks:  3-7 last 10

San Diego Padres:  5-5 last 10

The Diamondbacks are entering this series off a loss and lost their 3-game series against the Kansas City Royals 2-1 in their last series. They enter this game with a 44-46 record overall and have a road record of 21-21. This is the 2nd game of a 4-game series with the Padres on Tuesday with the series opener still to be played on Monday. Their offense ranks 4th in the MLB with a .772 OPS. Zac Gallen is their starting pitcher on Monday while Merrill Kelly is making his start in this game on Tuesday. He is 7-4 with a 3.55 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 3 ER, 1 HR, and 3 BB with 3 SO on 5 hits through 6 IP against the San Francisco Giants.

The Padres are entering this series off a win and won their 3-game series against the Texas Rangers 2-1 in their last series. They enter this game with a 48-41 record overall and have a home record of 27-15. This is the 2nd game of a 4-game series with the Diamondbacks on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 23rd in the MLB with a .690 OPS. Yu Darvish is their starting pitcher on Monday while Nick Pivetta is making his start in this game on Tuesday. He is 9-2 with a 3.25 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 1 homer, and 0 walks with 6 strikeouts on 7 hits through 6 innings pitched against the Philadelphia Phillies.

The current betting odds have the Padres listed as a slight favorite in this game according to Draftkings Sportsbook. The Padres have looked good in their games this season with their 48-41 record overall which has them right near the top of the NL West. They have also looked a lot better in their own ballpark this year with their 27-15 home record. Meanwhile, the Diamondbacks haven't looked great in their games this season with their 44-46 record overall which has them right near the bottom of the NL West. They haven't been a great road team either with their 21-21 road record this season. The Padres haven't been hot lately as they are only 5-5 in their last 10 games, but they did win their last series at home and have been hotter than the Diamondbacks who are only 3-7 in their last 10 games. Kelly is on the mound for the Diamondbacks in this one and he has looked good this season. He is 7-4 with a 3.55 ERA, but lately he has been giving up more runs in his starts. He did give up 3 earned runs in his last start which has been a common theme for him on the road, and even the team has lost 2 games in a row now with him starting. Pivetta is on the mound for the Padres in this one and he has been a solid starter for them all season. He is 9-2 with a 3.25 ERA and he hasn't been giving up many runs lately. He only gave up 1 earned run in his last start which is starting to become a common theme for him, and the team has won 2 games in a row with him starting too. Pivetta gives the edge to the Padres in this one at home, and the Padres have also looked like a much better team at home this year. The best way to place a bet here is on the Padres to win this game. 

Diamondbacks Padres Prediction:  Our MLB Pick for Tuesday, July 8, 2025 (9:40 pm ET start time) is Padres 4 Diamondbacks 1.

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Arizona Diamondbacks: 226-205 (+9.6 units) on the moneyline in all games. 113-100 (+24.9 units) on the moneyline in road games. 93-104 (+17 units) on the moneyline as an underdog of +100 or higher. 12-6 OVER vs. a starting pitcher whose winning percentage is better than 70%.

San Diego Padres: 117-89 (-8.8 units) on the moneyline in home games. 157-113 (-12.1 units) on the moneyline as a favorite of -110 or higher. 68-63 (-8.2 units) on the moneyline against division opponents. 37-22 OVER at home against division opponents.

Arizona Diamondbacks:  T. Henry (RP) Sixty Day IL - Ulnar Collateral Ligament. R. Thompson (RP) Fifteen Day IL - Scapular Strain. P. Smith (1B) Ten Day IL - Oblique. I. Vargas (2B) Ten Day IL - Foot. G. Moreno (C) Ten Day IL - Hand. C. Montes De Oca (RP) Sixty Day IL - Elbow. J. Martinez (RP) Sixty Day IL - Elbow. C. Mena (SP) Sixty Day IL - Shoulder. K. Graveman (RP) Fifteen Day IL - Hip. C. Burnes (SP) Sixty Day IL - Elbow. A. Puk (RP) Sixty Day IL - Elbow. J. Montgomery (SP) Sixty Day IL - Elbow. B. Walston (SP) Sixty Day IL - Elbow.

San Diego Padres:  R. Bergert (SP) Fifteen Day IL - Forearm. Y. Darvish (SP) Sixty Day IL - Elbow. M. King (SP) Fifteen Day IL - Shoulder. J. Brito (RP) Sixty Day IL - Forearm. J. Musgrove (SP) Sixty Day IL - Elbow.

“It's a great recognition. Just really, really happy to be in this position compared to the spot I was last year. I think it says a lot about the work that we both put in individually but as a group, too. I think when you talk about the individual accomplishments, accolades and being recognized, a lot of that is based on the work of the whole of our offense and I think it's really cool to be celebrated in that way and recognized, but I think to be able to represent kind of the whole is meaningful.” - Corbin Carroll on making the All-Star team as reserves this season. 

“There’s a consideration. It’s a one-run game at that point. It would’ve been more of a consideration if some of those guys were unavailable. But it fell into the category of, ‘Hey, [Hart] had done his job.’” - Mike Shildt after his team’s win against the Rangers in their game on Sunday.

Corbin Carroll (L) RF

Ketel Marte (S) 2B

Geraldo Perdomo (S) SS

Josh Naylor (L) 1B

Eugenio Suárez (R) 3B

Jake McCarthy (L) LF

Randal Grichuk (R) DH

Alek Thomas (L) CF

Jose Herrera (S) C

Fernando Tatis Jr. (R) RF

Jackson Merrill (L) CF

Manny Machado (R) 3B

Luis Arraez (L) 1B

Gavin Sheets (L) LF

Xander Bogaerts (R) SS

Jake Cronenworth (L) 2B

Trenton Brooks (L) DH

Martín Maldonado (R) C

Batting Average:  James McCann (.400)

Hits:  Josh Naylor (92)

Home Runs:  Eugenio Suárez (28)

RBI:  Eugenio Suárez (73)

Stolen Bases:  Geraldo Perdomo (13)

Wins:  Brandon Pfaadt (8)

Saves:  Shelby Miller (10)

ERA:  Christian Montes De Oca (0.00)

Batting Average:  Bryce Johnson (.313)

Hits:  Luis Arraez (99)

Home Runs:  Fernando Tatis (15)

RBI:  Manny Machado (52)

Stolen Bases:  Fernando Tatis (19)

Wins:  Nick Pivetta (9)

Saves:  Robert Suarez (25)

ERA:  Bradgley Rodriguez (0.00)

Managers:

Arizona Diamondbacks: Torey Lovullo (9th season)

San Diego Padres: Mike Shildt (2nd season)