by Rod Pearson
Friday, Nov 06, 2026
Game Time: 4:25 pm ET, Sunday, November 8, 2026
Venue: Lumen Field, Seattle, WA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Cardinals +8.5, Seahawks -8.5; Over/Under: 39.5 points
Bet365: Point Spread: Cardinals +8.5, Seahawks -8.5; Over/Under: 39.5 points
BetMGM: Point Spread: Cardinals +8.5, Seahawks -8.5; Over/Under: 39.5 points
Season Record
Arizona Cardinals: 3-5 (4th place, NFC West)
Seattle Seahawks: 4-4 (2nd place, NFC West)
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Recent Form
Arizona Cardinals: won their last game on the road against the Dallas Cowboys 33-30 in overtime.
Seattle Seahawks: lost their last game at home against the Chicago Bears 34-17.
Arizona Cardinals vs Seattle Seahawks Preview and Analysis
The Cardinals are entering this game with a 3-5 record overall and they have a 1-2 record in their divisional games too. They are 0-3 in their home games, 3-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Dallas Cowboys 33-30 in OT. Jacoby Brissett was the starting QB and he completed 10/23 passes for 119 passing yards, 0 touchdowns, and 1 interception before getting replaced by Gardner Minshew II who completed 17/23 passes for 188 yards and 3 TDs. Tyler Allgeier led the team in rushing yards with 147 and 1 TD. Michael Wilson led the receivers with 111 receiving yards on 8 receptions and 1 TD. Jack Gibbens led the defense in that game with 11 solo tackles while Josh Sweat, Andrew Billings, Zaven Collins, and L.J. Collier each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
The Seahawks are entering this game with a 4-4 record overall and they have a 1-1 record in their divisional games too. They are 3-2 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Chicago Bears 34-17. Sam Darnold was the starting QB and he completed 17/34 passes for 188 passing yards, 2 touchdowns, and 1 interception. Jadarian Price led the team in rushing yards with 29. Jaxon Smith-Njigba led the receivers with 118 receiving yards on 6 receptions and 1 TD. Ernest Jones IV led the defense in that game with 13 solo tackles while Mike Morris led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Cardinals vs Seahawks Prediction
The current betting odds have the Seahawks listed as an 8.5 point favorite in this game according to Draftkings Sportsbook. The Seahawks haven't looked great in their games this season with their 4-4 record overall, but that record has them right near the top of the NFC West. They have looked better on their home field too with their 3-2 home record this season. Meanwhile, the Cardinals haven't looked great in their games this season with their 3-5 record overall which has them right at the bottom of the NFC West. They have been a good road team though with their 3-2 road record this year. The Cardinals were supposed to be one of the worst teams in the NFL this season and they have looked a lot better than expected. Mike LaFleur has them looking like a competent football team which is something they haven't looked like in years. They are coming off another surprise win over the Cowboys 33-30 in OT, but they still aren't a good team with the talent that they have and this team has been taking 1 step forward and 2 steps back all year. Minshew came into the game last week to save the day, but now he is the starter and the Cardinals will do what they always do after a big win which is fall flat on their face. The Seahawks definitely haven't looked like the same team that won the Super Bowl last season, but they still have a lot more talent and will be looking to bounce back at home, coming off an embarrassing 34-17 loss to the Bears on Monday night. The Seahawks will be starting Drew Lock since Darnold is dealing with an injury, but Darnold hasn't looked that great this season anyway and the Seahawks already crushed the Cardinals in Arizona earlier this year with Lock at QB. Look for the Seahawks to do the same here in a nice bounce back game at home. The best way to place a bet here is on the Seahawks to cover the spread in this game.
Cardinals Seahawks Prediction: Our NFL Pick for Sunday, November 8, 2026 (4:25 pm ET start time) is Seahawks 24 Cardinals 7.
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NFL Betting Trends
Arizona Cardinals: 0-4 ATS revenging a same season loss against an opponent. 7-13 ATS after playing their last game on the road. 4-8 ATS after 1 or more consecutive wins. 11-5 OVER after allowing 30 points or more last game. 12-6 OVER after playing their last game on the road.
Seattle Seahawks: 10-5 ATS versus division opponents. 6-3 ATS when playing against a bad team (Win Pct. 25% to 40%). 16-11 ATS as a favorite. 12-5 OVER as a home favorite. 9-3 OVER when playing against a team with a losing record.
Key Injuries
Arizona Cardinals: M. Melton (CB) Injured - Knee. J. Brissett (QB) Injured - Other. B. Baker (S) Injured - Rest. I. Seumalo (OG) Injured - Rest. H. Froholdt (OG) Injured - Rest. J. Sweat (LB) Injured - Rest. J. Gaines II (OG) Injured - Ankle. M. Wilson (WR) Injured - Rest. B. Knight (RB) Injured - Concussion. I. Adams (OG) Injured - Ankle. W. Nolen III (DL) Injured - Ankle. R. Virgil (WR) Injured - Back. J. Williams (OG) Injured - Knee.
Seattle Seahawks: E. Jones IV (LB) Injured - Ankle. D. Hall (LB) Injured - Back. Q. Nelson (OG) Injured - Knee. U. Nwosu (LB) Injured - Ankle. S. Darnold (QB) Out - Quad. D. Lock (QB) Injured - Elbow. V. Jones Jr. (RB) Injured - Hamstring. B. Pili (DL) Injured - Back. R. Shaheed (WR) Injured - Knee. A. Bradford (OG) Injured - Knee. C. Cross (OT) Injured - Ankle. T. Knight (LB) Injured - Thigh. C. O'Toole (LB) Injured - Foot. T. Horton (WR) Injured - Hand. N. Emmanwori (S) Injured - Shoulder.
Notable Quotes
“I don’t think anyone really in this room or anyone, probably in the country, thought that we had a chance at a comeback right there. And so to make it 30-30, it was only fitting, and for Chad to finish it out for us. Like I told the guys, right when we started overtime, there’s no way we’re not coming out here with a win.” - Mike LaFleur after his team’s win against the Cowboys in their last game.
“We got beat. No other way to sugar coat it. When you look at the things that it takes to win in our league, we didn't do those things and they did.” - Mike Macdonald after his team’s loss against the Bears in their last game.
Starting Lineups
Arizona Cardinals
WR Fehoko, Simi
WR Wilson, Michael
WR Duvernay, Devin
TE McBride, Trey
QB Minshew II, Gardner
RB Allgeier, Tyler
Seattle Seahawks
WR Smith-Njigba, Jaxon
WR Shaheed, Rashid
WR Kupp, Cooper
TE Barner, AJ
QB Lock, Drew
RB Charbonnet, Zach
FB Russell, Brady
Statistical Leaders
Arizona Cardinals
Passing: Jacoby Brissett (1,719)
Rushing: Tyler Allgeier (323)
Receiving: Trey McBride (544)
Touchdowns: Trey McBride (5)
Seattle Seahawks
Passing: Sam Darnold (1,478)
Rushing: Emanuel Wilson (403)
Receiving: Jaxon Smith-Njigba (985)
Touchdowns: Jaxon Smith-Njigba (9)
Coaches:
Arizona Cardinals: Mike LaFleur (1st season)
Seattle Seahawks: Mike Macdonald (3rd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
