by Rod Pearson
Friday, Oct 31, 2025
Game Time: 8:15 pm ET, Monday, November 3, 2025
Venue: AT&T Stadium, Arlington, TX
Where to Watch: ESPN, ABC
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Cardinals +2.5, Cowboys -2.5; Over/Under: 54.5 points
Bet365: Point Spread: Cardinals +2.5, Cowboys -2.5; Over/Under: 53.5 points
BetMGM: Point Spread: Cardinals +2.5, Cowboys -2.5; Over/Under: 53.5 points
Season Record
Arizona Cardinals: 2-5 (4th place, NFC West)
Dallas Cowboys: 3-4-1 (2nd place, NFC East)
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Recent Form
Arizona Cardinals: lost their last game at home against the Green Bay Packers 27-23.
Dallas Cowboys: lost their last game on the road against the Denver Broncos 44-24.
Arizona Cardinals vs Dallas Cowboys Preview and Analysis
The Cardinals are entering this game with a 2-5 record overall and they have a 0-2 record in their divisional games too. They are 1-3 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Green Bay Packers 27-23. Jacoby Brissett was the starting QB and he completed 25/36 passes for 279 passing yards, 2 touchdowns, and 0 interceptions. Zonovan Knight led the team in rushing yards with 57. Trey McBride led the receivers with 74 receiving yards on 10 receptions and 2 TDs. Akeem Davis-Gaither and Budda Baker each led the defense in that game with 4 solo tackles and 4 assisted tackles while Zaven Collins led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
The Cowboys are entering this game with a 3-4-1 record overall and they have a 2-1 record in their divisional games too. They are 2-0-1 in their home games, 1-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Denver Broncos 44-24. Dak Prescott was the starting QB and he completed 19/31 passes for 188 passing yards, 0 touchdowns, and 2 interceptions. Javonte Williams led the team in rushing yards with 41 and 2 TDs. George Pickens led the receivers with 78 receiving yards on 7 receptions. Alijah Clark led the defense in that game with 4 solo tackles and 2 assisted tackles while no one on the defense recorded a sack for them. Trikweze Bridges came away with the only interception for them in that one.
Cardinals vs Cowboys Prediction
The current betting odds have the Cowboys listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Cowboys haven't looked great in their games this season with their 3-4-1 record overall, but that record has them near the top of the NFC East. They are off a 44-24 loss to the Broncos in their last one, but they have looked a lot better on their home field this year with their 2-0-1 home record. Meanwhile, the Cardinals haven't looked good in their games this season with their 2-5 record overall which has them right at the bottom of the NFC West. They are off a 27-23 loss to the Packers in their last one and they have been missing Kyler Murray in 2 of their games. This offense hasn't looked great this season even with Murray playing though. They have been dealing with a ton of injuries to their back field too and their defense has blown a few leads this season. The Cowboys have one of the worst defenses in the NFL this season with the points they have been giving up in every game so the Cardinals will be able to move the ball here, but they still won't be able to compete with this offense on the road. The Cowboys have a terrible defense, but they have one of the best offenses in the NFL that has been putting up a ton of points in every game and this is definitely a team they can outscore with the weapons they have. The best way to place a bet here is on the Cowboys to cover the spread in this game.
Cardinals Cowboys Prediction: Our NFL Pick for Monday, November 3, 2025 (8:15 pm ET start time) is Cowboys 42 Cardinals 17.
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NFL Betting Trends
Arizona Cardinals: 24-17 ATS in all games. 9-2 ATS as a road underdog of 7 points or less. 7-4 ATS after a loss by 6 or less points. 8-2 OVER after a loss by 6 or less points. 9-2 OVER when playing against a team with a losing record. 5-0 OVER vs. bad defensive teams who give up 24 or more points/game.
Dallas Cowboys: 1-4 ATS against NFC West division opponents. 3-7 ATS in all games where the total is greater than or equal to 49.5. 4-0 OVER against NFC West division opponents. 26-16 OVER in all games. 9-3 OVER in a home game where the total is greater than or equal to 45.5.
Key Injuries
Arizona Cardinals: Z. Jones (WR) Injured - Knee. K. Beachum (OG) Injured - Rest. K. Murray (QB) Injured - Foot. E. Demercado (RB) Injured - Ankle. G. Williams (CB) Injured - Knee. B. Ojulari (LB) Injured - Knee. K. Crawford (S) Injured - Ankle. W. Nolen III (DL) Injured - Calf.
Dallas Cowboys: K. Clark (DL) Injured - Elbow. D. Wilson (S) Injured - Elbow. D. Overshown (LB) Injured - Knee. J. Sanborn (LB) Injured - Groin. T. Smith (OG) Injured - Knee. P. Winfrey (DL) Injured - Back. J. Thomas (S) Injured - Migraine. R. Steward (CB) Injured - Thigh. C. Beebe (C) Injured - Ankle. M. Kneeland (DL) Injured - Ankle. A. Clark (CB) Injured - Ribs. S. Revel Jr. (CB) Injured - Knee. A. Cornelius (OT) Injured - Knee.
Notable Quotes
“I've got to do a better job at the end of the game and making the right decisions. There are some throws that more than likely could have changed the outcome of this game.” - Jacoby Brissett after their loss against the Packers in their last game.
“We’ve got to find a way to be consistent, whether it’s at home, on the road, regardless, we’re too good. We got too many good players. We’ve got great coaches. (Jadeveon Clowney) was just saying in the locker room this roster should not be going up and down like we’re doing, and a guy like that, when he says it ... that’s real, and so we’ve just got to look in the mirror.” - Dak Prescott after their loss against the Broncos in their last game.
Starting Lineups
Arizona Cardinals
WR Harrison Jr., Marvin
WR Jones, Zay
WR Wilson, Michael
TE McBride, Trey
QB Brissett, Jacoby
RB Knight, Bam
Dallas Cowboys
WR Pickens, George
WR Lamb, CeeDee
WR Turpin, KaVontae
TE Ferguson, Jake
QB Prescott, Dak
RB Williams, Javonte
FB Luepke, Hunter
Statistical Leaders
Arizona Cardinals
Passing: Kyler Murray (962)
Rushing: Kyler Murray (173)
Receiving: Trey McBride (421)
Touchdowns: Trey McBride (4)
Dallas Cowboys
Passing: Dak Prescott (2,069)
Rushing: Javonte Williams (633)
Receiving: George Pickens (685)
Touchdowns: Javonte Williams (9)
Coaches:
Arizona Cardinals: Jonathan Gannon (3rd season)
Dallas Cowboys: Brian Schottenheimer (1st season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
