American League vs National League Prediction, Preview and Odds - 07/14/2026

Game Time: 8:00 pm ET, Tuesday, July 14, 2026

Venue:  Citizens Bank Park, Philadelphia, PA

Where to Watch:  FOX

DraftKings:  Moneyline odds:  American League +120, National League -140; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  American League +120, National League -140; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  American League +120, National League -140; Over/Under:  7.5 runs

American League:  196-237 against National League opponents this season.

National League:  237-196 against American League opponents this season.

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American League:  48-45-2 against National League in All Star games.

National League:  45-48-2 against American League in All Star games.

The American League is entering this All-Star game off a loss last year after winning the year before that. The America League has now lost 2 of the last 3 years against the National League, but the American League had won 9 straight All-Star games before that and they will be looking to bounce back now. The American League has 3 of their players in the starting lineup, Yordan Alvarez, Ben Rice, and Junior Caminero, who are all in the top 4 in the MLB for home runs this season. They also have 2 of their starters, Yordan Alvarez and Ben Rice, in the top 3 of the MLB for OPS. The National League has a lot of good starting pitching on their side and does have the edge in that area, but the American League definitely has the better bullpen with some very good relief pitchers like Cade Smith and Bryan Baker who are both top 2 in the MLB this season in saves.

The National League is entering this All-Star game off a win last year after losing the season before that. They have now won 2 of the last 3 years against the American League and will be looking to build their own streak now after losing 9 straight All-Star Games to the American League before this run of 2 wins in the last 3 years. The American League has dominated the National League for so many years, but the tide is starting to turn now and the National League has clearly been better than the American League this season as a whole. The National League has 2 of their reserve players leading the league in batting average, Otto Lopez and Luis Arraez. Those 2 also lead the league in hits and the National League does have the home run leader too, Kyle Schwarber. They also have the superior pitching staff with 4 of their starting pitchers being in the top 7 of the MLB for wins and 2 of their starters are in the top 3 of the league for ERA this season, Jacob Misiorowski and Chris Sale. The National League has clearly been the better league this season and they are going to have an advantage in this game with their offense and their starting pitchers.

The current betting odds have the National League listed as a favorite in this game according to Draftkings Sportsbook. The National League has had a lot of trouble against the American League in this game over the years, but they have clearly been the better league this season. The teams in the National League combined have 41 more wins over American League teams than losses this season and that has been evident by the Wild Card race in each league. The American League has dominated the National League over the last 12 years and even had a 9 game winning streak at one point, but that is starting to change now with the National League coming off a win last season and winning 2 of the last 3 years now. The teams in the National League have not only been better than the American League as a whole, the players have too. The American League does have a bit of an advantage later in this game as they do have the better relief pitchers, but the National League also has a lot of talent with their starting pitchers which will counter the American League's advantage with the bullpen. The American League does have 2 of the best players in the league when it comes to slugging, but they don't have much after that. The players in the National League have been racking up hits and RBI's all season which is going to be a big part of this game. These games have also been very pitcher dominated over the last few years with a lot of lower scoring games, but the last 2 have seen that start to change. With the offensive talent in the National League this season, this could turn into a higher scoring games, especially since the American League will have more questionable starters going in the 1st half. Look for the National League to finally win 2 games in a row against the American League for the first time in over a decade, and look for this to be a higher scoring game too. The best way to place a bet here is on the National League to win this game and on the over. 

American League National League Prediction:  Our MLB Pick for Tuesday, July 14, 2026 (8:00 pm ET start time) is National League 6 American League 3.

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American League: 10-2 on the moneyline in the last 12 All-Star games. 22-5-1 on the moneyline in the last 28 All-Star games. 4-2 to the under 7.5 runs in the last 6 All-Star games. 6-3 to the under 7.5 runs in the last 9 All-Star games. 

National League: 2-10 on the moneyline in the last 12 All-Star games. 5-22-1 on the moneyline in the last 28 All-Star games. 4-2 to the under 7.5 runs in the last 6 All-Star games. 6-3 to the under 7.5 runs in the last 9 All-Star games. 

American League:  Vladimir Guerrero Jr. (TOR), Nick Kurtz (ATH), Aaron Judge (NYY), Byron Buxton (MIN), Cam Schlittler (NYY), Ranger Suarez (BOS).

National League:  Shohei Ohtani (LAD), Jacob Misiorowski (MIL), Zack Wheeler (PHI), Chase Burns (CIN).

“In the playoffs last year, I tried to take a couple of minutes each day to go, ‘... this is really cool.’ It’s going to be easier to do that in an All-Star Game, though. The result doesn’t matter. This is something that not many people get to be a part of. I’ve definitely thought about that 13th-round pick in Auburn, New York. The road I’ve been down to lead me to this job, to be able to manage the American League in the All-Star Game and be just the second dude in this organization besides Cito [Gaston] to do that. I’ve taken some time to think about that.” - John Schneider on managing the American League team in the All-Star Game. 

"I think he deserves it. He’s the hometown ballplayer and I think the city of Philly will enjoy watching him and supporting him. I had a conversation with him this morning. He was very grateful. In a time when guys are not wanting to participate, this guy in the Midsummer Classic for fans, I think this is a good thing. He’s very excited about pitching." - Dave Roberts on starting Cristopher Sanchez for the National League team in the All-Star Game. 

C: Shea Langeliers (ATH)

1B: Ben Rice (NYY)

2B: Ernie Clement (TOR)

3B: Junior Caminero (TB)

SS: Bobby Witt Jr. (KC)

OF: Mike Trout (LAA)

OF: Riley Greene (DET)

OF: Cody Bellinger (NYY)

DH: Yordan Alvarez (HOU)

C: Drake Baldwin (ATL)

1B: Freddie Freeman (LAD)

2B: Ozzie Albies (ATL)

3B: Max Muncy (LAD)

SS: CJ Abrams (WSH)

OF: Brandon Marsh (PHI)

OF: Juan Soto (NYM)

OF: Andy Pages (LAD)

DH: Kyle Schwarber (PHI)

C: Dillon Dingler (DET)

C: Adley Rutschman (BAL)

INF: Travis Bazzana (CLE)

INF: Willson Contreras (BOS) 

INF: Kevin McGonigle (DET)

INF: Miguel Vargas (CWS)

INF: Munetaka Murakami (CWS) 

OF: Randy Arozarena (SEA)

OF: Ceddanne Rafaela (BOS) 

OF: Tristan Peters (CWS) 

DH: Yandy Díaz (TB)

C: William Contreras (MIL)

C: Hunter Goodman (COL)

INF: Luis Arraez (SF)

INF: Bryce Harper (PHI)

INF: Otto Lopez (MIA)

INF: Matt Olson (ATL)

INF: Sal Stewart (CIN)

OF: Corbin Carroll (AZ)

OF: Pete Crow-Armstrong (CHC)

OF: Jordan Walker (STL)

OF: James Wood (WSH)

DH: Iván Herrera (STL) 

RHP: Dylan Cease (TOR)

LHP: Parker Messick (CLE)

RHP: Nick Martinez (TB) 

RHP: Drew Rasmussen (TB)

RHP: Joe Ryan (MIN)

RHP: Cam Schlittler (NYY)

LHP: Ranger Suarez (BOS)

RHP: Michael Wacha (KC)

RHP: Braxton Ashcraft (PIT) 

RHP: Chase Burns (CIN)

LHP: Jesús Luzardo (PHI) 

RHP: Max Meyer (MIA)

RHP: Jacob Misiorowski (MIL)

LHP: Eduardo Rodriguez (AZ)

LHP: Chris Sale (ATL)

LHP: Cristopher Sánchez (PHI)

RHP: Paul Skenes (PIT)

RHP: Logan Webb (SF)

RHP: Yoshinobu Yamamoto (LAD)

LHP: Justin Wrobleski (LAD) 

LHP: Foster Griffin (WSH) 

RHP: Bryan Baker (TB)

LHP: Aroldis Chapman (BOS)

LHP: Jacob Latz (TEX)

RHP: Cade Smith (CLE)

RHP: Louis Varland (TOR)

RHP: Jhoan Duran (PHI)

RHP: Raisel Iglesias (ATL)

RHP: Mason Miller (SD)

RHP: Riley O'Brien (STL) 

Batting Average:  Yandy Díaz (.322)

Hits:  Yordan Alvarez (111)

Home Runs:  Yordan Alvarez (31)

RBI:  Yordan Alvarez (70)

Stolen Bases:  Bobby Witt (30)

Wins:  Cam Schlittler (9)

Saves:  Cade Smith (28)

ERA:  Cam Schlittler (2.05)

Batting Average:  Otto Lopez (.334)

Hits:  Otto Lopez (127)

Home Runs:  Kyle Schwarber (32)

RBI:  Jordan Walker (74)

Stolen Bases:  Pete Crow-Armstrong (24)

Wins:  Chase Burns (11)

Saves:  Mason Miller (25)

ERA:  Jacob Misiorowski (1.62)

Managers:

American League: John Schneider (Toronto Blue Jays)

National League: Dave Roberts (Los Angeles Dodgers)